ID D3V1D4_XENBS Unreviewed; 649 AA.
AC D3V1D4;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Putative Tyrosine decarboxylase {ECO:0000313|EMBL:CBJ81478.1};
DE EC=4.1.1.25 {ECO:0000313|EMBL:CBJ81478.1};
GN OrderedLocusNames=XBJ1_2352 {ECO:0000313|EMBL:CBJ81478.1};
OS Xenorhabdus bovienii (strain SS-2004).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ81478.1, ECO:0000313|Proteomes:UP000002045};
RN [1] {ECO:0000313|EMBL:CBJ81478.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ81478.1};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:E27909-E27909(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR602129-50};
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DR EMBL; FN667741; CBJ81478.1; -; Genomic_DNA.
DR RefSeq; WP_012988791.1; NC_013892.1.
DR AlphaFoldDB; D3V1D4; -.
DR STRING; 406818.XBJ1_2352; -.
DR KEGG; xbo:XBJ1_2352; -.
DR PATRIC; fig|406818.4.peg.2115; -.
DR eggNOG; COG0076; Bacteria.
DR HOGENOM; CLU_005446_0_1_6; -.
DR Proteomes; UP000002045; Chromosome.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0004837; F:tyrosine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR021115; Pyridoxal-P_BS.
DR InterPro; IPR049373; TyrDC_C.
DR PANTHER; PTHR42735; -; 1.
DR PANTHER; PTHR42735:SF4; TYROSINE DECARBOXYLASE; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR Pfam; PF21391; tyr_de_CO2_C; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00392; DDC_GAD_HDC_YDC; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CBJ81478.1};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50}.
FT DOMAIN 486..626
FT /note="L-tyrosine decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21391"
FT MOD_RES 397
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ SEQUENCE 649 AA; 73999 MW; 205128E3BB8F1C81 CRC64;
MTKPLYTNLN VDALFLGPKS ENAVFFREMM DYAVSEHMHW RSGFHPEDAT LVTSVDRYEH
NYRETLYRTE GILNQLSAKL KNTSIPFFSP RYLGHINSDT LMVSNLAYVM AMMYNPNNCT
YEVSPTTTEL ELESGLDLCR MLGYDPQRAW GHITSGGTVA NYEGLWVARN LKTLPFAVSQ
HPETKELVSH KSQKQLMNMP TAEVLDLISE LQRRGIFDEI RNMTCRGTGS KTEILGKLLV
PQSKHYSWMK AADILGIGQE NIIPLPVNEH YQTDIGKMRE ITFDLIEKGE PILAMIGVVG
TTEVGAIDRI DEVIALRQEC EERYGESFYI HVDAAYAGYA CSMLLNEQGE FMEYDDLVNY
HHTLGIIPEN ISWPKPEVYQ SFKALRYVDS ITVDPHKVGF IQYSAGAICM KDKRILDLIS
SRALYVFEEN DNQSNFPASN RGILGASIME GSKAGATAAA LWAAHRLLPL NISGYGKVIA
AGIVTANQLL DKMANMLPIE VGEYRFKMYI MPTPDFHMIN FTFKEVGNAS LINHNALNKR
IYELCSYSSG RAYSNDFLTS STILDYKEYG DTPWYYAEKC GFSRSEWENT HRVYVLRAAV
MTHCLRNPEH FDEYWKQLQT IFAKKLTQLV DEEEKKSRQI LNREESFLN
//
