ID D3V9T6_XENNA Unreviewed; 415 AA.
AC D3V9T6;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Esterase FrsA {ECO:0000256|HAMAP-Rule:MF_01063};
DE EC=3.1.1.1 {ECO:0000256|HAMAP-Rule:MF_01063};
GN Name=yafA {ECO:0000313|EMBL:CBJ89324.1};
GN Synonyms=frsA {ECO:0000256|HAMAP-Rule:MF_01063};
GN OrderedLocusNames=XNC1_1253 {ECO:0000313|EMBL:CBJ89324.1};
OS Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG
OS 1036 / NCIMB 9965 / AN6).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ89324.1, ECO:0000313|Proteomes:UP000008075};
RN [1] {ECO:0000313|EMBL:CBJ89324.1, ECO:0000313|Proteomes:UP000008075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 /
RC AN6 {ECO:0000313|Proteomes:UP000008075};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:E27909-E27909(2011).
CC -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000256|HAMAP-
CC Rule:MF_01063}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01063};
CC -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000256|HAMAP-
CC Rule:MF_01063}.
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DR EMBL; FN667742; CBJ89324.1; -; Genomic_DNA.
DR RefSeq; WP_013183746.1; NC_014228.1.
DR AlphaFoldDB; D3V9T6; -.
DR STRING; 406817.XNC1_1253; -.
DR ESTHER; xenna-d3v9t6; Duf_1100-R.
DR KEGG; xne:XNC1_1253; -.
DR eggNOG; COG1073; Bacteria.
DR HOGENOM; CLU_036819_0_0_6; -.
DR Proteomes; UP000008075; Chromosome.
DR GO; GO:0106435; F:carboxylesterase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR HAMAP; MF_01063; FrsA; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR043423; FrsA.
DR InterPro; IPR010520; FrsA-like.
DR PANTHER; PTHR22946:SF4; DLH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22946; UNCHARACTERIZED; 1.
DR Pfam; PF06500; FrsA-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01063, ECO:0000313|EMBL:CBJ89324.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487, ECO:0000256|HAMAP-
KW Rule:MF_01063}.
SQ SEQUENCE 415 AA; 47469 MW; 53AB7537BDE3E27A CRC64;
MTKKNLSESL FKPWFKHRET STLVKFIRPQ SVTASDSMLG GERREHWYRM INWLAWIWRG
IDSLEIQDIL SRIAVTDAER STDHLLDTVI GYRKGNWAFE WSQLAMQWQQ EALRAEEAEQ
AGACWLKAST LYSIAAYPHL RGDELADQAI VLANKAYENA ARFFDYELKK LEFQLEDGKS
VTGLLHIPSR VKEPCPTILV CASLDNVQSD CWRLFREHFS PLGFAMLTLD MPAVGYSAKF
TLTQDTCVLH QQVLQQLNSV PWIDHTRIGV FGFRFGANIA VRLAYLEPKL IKGISVVGPI
VHELLHDEKR QQKIPSMYID VLASRLGIYH IDENRLRSEL GYYSLKNQGL LGRRCSVPML
SVYWEDDIFS PRKDSKLIAM SSIDGSLKAI PATSIYGGFN KALHEISVWL KDKVL
//
