ID   D3VEZ4_XENNA            Unreviewed;       238 AA.
AC   D3VEZ4;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Phosphate-specific transport system accessory protein PhoU {ECO:0000256|ARBA:ARBA00017264, ECO:0000256|PIRNR:PIRNR003107};
GN   Name=phoU {ECO:0000313|EMBL:CBJ92451.1};
GN   OrderedLocusNames=XNC1_4429 {ECO:0000313|EMBL:CBJ92451.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG
OS   1036 / NCIMB 9965 / AN6).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ92451.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|EMBL:CBJ92451.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 /
RC   AN6 {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA   Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA   Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA   Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA   Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA   Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA   Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA   van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA   Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA   Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT   convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:E27909-E27909(2011).
CC   -!- FUNCTION: Part of the phosphate (Pho) regulon, which plays a key role
CC       in phosphate homeostasis. PhoU is essential for the repression of the
CC       Pho regulon at high phosphate conditions.
CC       {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR003107}.
CC   -!- SIMILARITY: Belongs to the PhoU family. {ECO:0000256|ARBA:ARBA00008107,
CC       ECO:0000256|PIRNR:PIRNR003107}.
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DR   EMBL; FN667742; CBJ92451.1; -; Genomic_DNA.
DR   RefSeq; WP_010848382.1; NC_014228.1.
DR   AlphaFoldDB; D3VEZ4; -.
DR   STRING; 406817.XNC1_4429; -.
DR   KEGG; xne:XNC1_4429; -.
DR   eggNOG; COG0704; Bacteria.
DR   HOGENOM; CLU_078518_2_1_6; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030643; P:intracellular phosphate ion homeostasis; IEA:InterPro.
DR   GO; GO:0045936; P:negative regulation of phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028366; P_transport_PhoU.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   NCBIfam; TIGR02135; phoU_full; 1.
DR   PANTHER; PTHR42930; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR   PANTHER; PTHR42930:SF3; PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU; 1.
DR   Pfam; PF01895; PhoU; 2.
DR   PIRSF; PIRSF003107; PhoU; 1.
DR   SUPFAM; SSF109755; PhoU-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR003107};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW   ECO:0000256|PIRNR:PIRNR003107};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW   Transport {ECO:0000256|PIRNR:PIRNR003107}.
FT   DOMAIN          26..112
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
FT   DOMAIN          129..212
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
SQ   SEQUENCE   238 AA;  27522 MW;  75E9BEA362464FF6 CRC64;
     MDNLNLSKHI SGQFTAELEH IRTELMTMGG LVEEQLRNAI LSMHNQDKML ARQVIEDDRK
     VNMMEVAIDE ACVRIIAKRQ PTASDLRLIM VISKTIAELE RIGDVAKKIC QTALEKFSHQ
     QQSLLVSLES LGNHTIQMLH DVLDAFARMD LDEAVRIYHE DKKVDQEYEG IVRQLMTYMM
     EDPRTIPNVM TALFCARSIE RIGDRCQNIC EFIFYYVKGQ DFRHVGGDEL EKFLTKKE
//