ID D3YVB0_MOUSE Unreviewed; 180 AA.
AC D3YVB0;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Lipase, family member N {ECO:0000313|Ensembl:ENSMUSP00000114551.2};
DE Flags: Fragment;
GN Name=Lipn {ECO:0000313|Ensembl:ENSMUSP00000114551.2,
GN ECO:0000313|MGI:MGI:1917416};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114551.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000114551.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114551.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000114551.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114551.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3YVB0; -.
DR SMR; D3YVB0; -.
DR ESTHER; mouse-LIPN; Acidic_Lipase.
DR Antibodypedia; 48305; 85 antibodies from 12 providers.
DR Ensembl; ENSMUST00000126710.8; ENSMUSP00000114551.2; ENSMUSG00000024770.15.
DR AGR; MGI:1917416; -.
DR MGI; MGI:1917416; Lipn.
DR VEuPathDB; HostDB:ENSMUSG00000024770; -.
DR GeneTree; ENSGT00940000161695; -.
DR HOGENOM; CLU_100445_0_0_1; -.
DR OMA; MFGTKGF; -.
DR ChiTaRS; Lipn; mouse.
DR Proteomes; UP000000589; Chromosome 19.
DR Bgee; ENSMUSG00000024770; Expressed in lumbar subsegment of spinal cord and 14 other cell types or tissues.
DR ExpressionAtlas; D3YVB0; baseline and differential.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR PANTHER; PTHR11005:SF16; LIPASE MEMBER N; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..180
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008413267"
FT DOMAIN 39..99
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT NON_TER 180
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000114551.2"
SQ SEQUENCE 180 AA; 20284 MW; AB847F7F3DAF46F1 CRC64;
MPMMWLFLTT ACLIPGTLSA GGFLDFENKV NPEVWMNASE IIMYNGYPSE EYDVTTADGY
ILAINRIPHG RAQTGQTGPR PVVYMQHALF ADNAYWLENF ANGSLGFILA DAGYDVWMGN
SRGNTWSRRH KTLSANEEKF WAFSFNEMAK YDLPGIIDFI VNKTGQEKLY FIGHSLGTTI
//
