ID D3YVQ1_MOUSE Unreviewed; 258 AA.
AC D3YVQ1;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Interaction protein for cytohesin exchange factors 1 {ECO:0000313|Ensembl:ENSMUSP00000114267.2};
DE Flags: Fragment;
GN Name=Ipcef1 {ECO:0000313|Ensembl:ENSMUSP00000114267.2,
GN ECO:0000313|MGI:MGI:2444159};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114267.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000114267.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114267.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000114267.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114267.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3YVQ1; -.
DR SMR; D3YVQ1; -.
DR MaxQB; D3YVQ1; -.
DR PeptideAtlas; D3YVQ1; -.
DR ProteomicsDB; 304387; -.
DR Antibodypedia; 33399; 141 antibodies from 18 providers.
DR Ensembl; ENSMUST00000145156.8; ENSMUSP00000114267.2; ENSMUSG00000064065.16.
DR AGR; MGI:2444159; -.
DR MGI; MGI:2444159; Ipcef1.
DR VEuPathDB; HostDB:ENSMUSG00000064065; -.
DR GeneTree; ENSGT00940000154428; -.
DR HOGENOM; CLU_1079852_0_0_1; -.
DR ChiTaRS; Ipcef1; mouse.
DR Proteomes; UP000000589; Chromosome 10.
DR Bgee; ENSMUSG00000064065; Expressed in animal zygote and 101 other cell types or tissues.
DR ExpressionAtlas; D3YVQ1; baseline and differential.
DR CDD; cd01260; PH_CNK_mammalian-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12844:SF45; CNK3_IPCEF1 FUSION PROTEIN-RELATED; 1.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D3YVQ1,
KW ECO:0007829|MaxQB:D3YVQ1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 36..135
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 143..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 258
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000114267.2"
SQ SEQUENCE 258 AA; 29017 MW; 151ED4EC91120ED8 CRC64;
MATEGNQVPL RQKPRKKTQG FFNMSRRRIS CKDLGHADCQ GWLYKKKEKG TFLSNKWKKF
WVVLKGSSLY WYSNQMAEKA DGFVNLSDFT VERASECKKK NAFKINHPQI KAFYFAAENL
QEMNVWLNKL GFAVTHQESI TKDEECYSES EQEDPEVAVE APPPPYASTT SSPVAAQWAS
SSSPKRRETS CSFSSLENTV KAPSQFSSSG SKERQSWHNI VNSSPATEDA GLPLTFAEQV
HTLAFSEASN CQAPENNC
//
