ID D3YW49_MOUSE Unreviewed; 495 AA.
AC D3YW49;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Teneurin transmembrane protein 3 {ECO:0000313|Ensembl:ENSMUSP00000105975.2};
GN Name=Tenm3 {ECO:0000313|Ensembl:ENSMUSP00000105975.2,
GN ECO:0000313|MGI:MGI:1345183};
GN Synonyms=Odz3 {ECO:0000313|MGI:MGI:1345183};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000105975.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000105975.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000105975.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000105975.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000105975.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; D3YW49; -.
DR SMR; D3YW49; -.
DR MaxQB; D3YW49; -.
DR PeptideAtlas; D3YW49; -.
DR ProteomicsDB; 312505; -.
DR Antibodypedia; 28699; 103 antibodies from 25 providers.
DR Ensembl; ENSMUST00000110346.9; ENSMUSP00000105975.2; ENSMUSG00000031561.17.
DR UCSC; uc009lru.1; mouse.
DR AGR; MGI:1345183; -.
DR MGI; MGI:1345183; Tenm3.
DR VEuPathDB; HostDB:ENSMUSG00000031561; -.
DR GeneTree; ENSGT01030000234566; -.
DR HOGENOM; CLU_017739_0_0_1; -.
DR ChiTaRS; Tenm3; mouse.
DR Proteomes; UP000000589; Chromosome 8.
DR Bgee; ENSMUSG00000031561; Expressed in optic fissure and 255 other cell types or tissues.
DR ExpressionAtlas; D3YW49; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR041161; EGF_Tenascin.
DR InterPro; IPR009471; Ten_N.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR11219:SF65; TENEURIN-3; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF18720; EGF_Tenascin; 1.
DR Pfam; PF06484; Ten_N; 1.
DR SMART; SM00181; EGF; 7.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS51361; TENEURIN_N; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|MaxQB:D3YW49,
KW ECO:0007829|PeptideAtlas:D3YW49};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..37
FT /note="Teneurin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51361"
FT DOMAIN 338..370
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 372..405
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 360..369
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 395..404
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 495 AA; 53665 MW; 78CCBF2C4E51D6CA CRC64;
MASGSVYSPP TRPLPRNTLS RSAFKFKKSS KYCSWRCTAL CAVGVSVLLA ILLSYFIAMH
LFGLNWHLQQ TENDTFENGK VNSDTVPTNT VSLPSGDNGK LGGFTHENNT IDSGELDIGR
RAIQEVPPGI FWRSQLFIDQ PQFLKFNISL QKDALIGVYG RKGLPPSHTQ YDFVELLDGS
RLIAREQRNL VESERAGRQA RSVSLHEAGF IQYLDSGIWH LAFYNDGKNP EQVSFNTIVI
ESVVECPRNC HGNGECVSGT CHCFPGFLGP DCSRAACPVL CSGNGQYSKG RCLCFSGWKG
TECDVPTTQC IDPQCGGRGI CIMGSCACNS GYKGENCEEA DCLDPGCSNH GVCIHGECHC
NPGWGGSNCE ILKTMCADQC SGHGTYLQES GSCTCDPNWT GPDCSNEICS VDCGSHGVCM
GGSCRCEEGW TGPACNQRAC HPRCAEHGTC KDGKCECSQG WNGEHCTIGR PTRLLASYLL
HFLFCAGTKP RPNSP
//
