ID D3YX04_MOUSE Unreviewed; 80 AA.
AC D3YX04;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=PMS1 homolog 1, mismatch repair system component {ECO:0000313|Ensembl:ENSMUSP00000120670.2};
DE Flags: Fragment;
GN Name=Pms1 {ECO:0000313|Ensembl:ENSMUSP00000120670.2,
GN ECO:0000313|MGI:MGI:1202302};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120670.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000120670.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120670.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000120670.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120670.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR AlphaFoldDB; D3YX04; -.
DR SMR; D3YX04; -.
DR MaxQB; D3YX04; -.
DR ProteomicsDB; 318887; -.
DR Antibodypedia; 4133; 380 antibodies from 32 providers.
DR Ensembl; ENSMUST00000126590.2; ENSMUSP00000120670.2; ENSMUSG00000026098.14.
DR AGR; MGI:1202302; -.
DR MGI; MGI:1202302; Pms1.
DR VEuPathDB; HostDB:ENSMUSG00000026098; -.
DR GeneTree; ENSGT00940000157085; -.
DR OMA; HRCEDPE; -.
DR ChiTaRS; Pms1; mouse.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000026098; Expressed in secondary oocyte and 168 other cell types or tissues.
DR ExpressionAtlas; D3YX04; baseline and differential.
DR GO; GO:0032389; C:MutLalpha complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0019899; F:enzyme binding; ISO:MGI.
DR GO; GO:0006298; P:mismatch repair; IMP:MGI.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF54; PMS1 PROTEIN HOMOLOG 1; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D3YX04,
KW ECO:0007829|ProteomicsDB:D3YX04};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT NON_TER 80
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000120670.2"
SQ SEQUENCE 80 AA; 8648 MW; C22AE1BF5B4694C8 CRC64;
MKQLPAATVR LLSSSQTITS VVSVVKELIE NSLDAGATSI EVKLENYGFD KIEIRDNGEG
IKAVDVPVMA VKYYTSKISS
//
