ID D3Z2D1_MOUSE Unreviewed; 234 AA.
AC D3Z2D1;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Leucine rich repeat containing 4B {ECO:0000313|Ensembl:ENSMUSP00000119374.2};
DE Flags: Fragment;
GN Name=Lrrc4b {ECO:0000313|Ensembl:ENSMUSP00000119374.2,
GN ECO:0000313|MGI:MGI:3027390};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119374.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000119374.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119374.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000119374.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119374.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z2D1; -.
DR SMR; D3Z2D1; -.
DR MaxQB; D3Z2D1; -.
DR PeptideAtlas; D3Z2D1; -.
DR ProteomicsDB; 361331; -.
DR Antibodypedia; 53687; 96 antibodies from 19 providers.
DR Ensembl; ENSMUST00000156093.2; ENSMUSP00000119374.2; ENSMUSG00000047085.15.
DR AGR; MGI:3027390; -.
DR MGI; MGI:3027390; Lrrc4b.
DR VEuPathDB; HostDB:ENSMUSG00000047085; -.
DR GeneTree; ENSGT00940000160261; -.
DR HOGENOM; CLU_1168197_0_0_1; -.
DR OMA; HYNNNTT; -.
DR ChiTaRS; Lrrc4b; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000047085; Expressed in embryonic brain and 100 other cell types or tissues.
DR ExpressionAtlas; D3Z2D1; baseline and differential.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF102; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 1: Evidence at protein level;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Proteomics identification {ECO:0007829|MaxQB:D3Z2D1,
KW ECO:0007829|PeptideAtlas:D3Z2D1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..234
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003052410"
FT DOMAIN 58..92
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT NON_TER 234
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000119374.2"
SQ SEQUENCE 234 AA; 25837 MW; 61CD0F3A5B4449DD CRC64;
MAQAHIRGSP CPLLPPGRMS WPHGALLLLW LFSPPLRAGG GGVAVTSAAG GGSPPATSCP
AACSCSNQAS RVICTRRELA EVPASIPVNT RYLNLQENSI QVIRTDTFKH LRHLEILQLS
KNLVRKIEVG AFNGLPSLNT LELFDNRLTT VPTQAFEYLS KLRELWLRNN PIESIPSYAF
NRVPSLRRLD LGELKRLEYI SEAAFEGLVN LRYLNLGMCN LKDIPNLTAL VRLE
//
