ID D3Z4A5_MOUSE Unreviewed; 107 AA.
AC D3Z4A5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Protein kinase, cAMP dependent regulatory, type I beta {ECO:0000313|Ensembl:ENSMUSP00000122693.2};
DE Flags: Fragment;
GN Name=Prkar1b {ECO:0000313|Ensembl:ENSMUSP00000122693.2,
GN ECO:0000313|MGI:MGI:97759};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122693.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122693.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122693.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000122693.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122693.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z4A5; -.
DR SMR; D3Z4A5; -.
DR MaxQB; D3Z4A5; -.
DR ProteomicsDB; 302586; -.
DR Antibodypedia; 10769; 400 antibodies from 32 providers.
DR Ensembl; ENSMUST00000155833.8; ENSMUSP00000122693.2; ENSMUSG00000025855.14.
DR AGR; MGI:97759; -.
DR MGI; MGI:97759; Prkar1b.
DR VEuPathDB; HostDB:ENSMUSG00000025855; -.
DR GeneTree; ENSGT00940000157513; -.
DR OMA; QILAWQK; -.
DR Proteomes; UP000000589; Chromosome 5.
DR Bgee; ENSMUSG00000025855; Expressed in substantia nigra and 280 other cell types or tissues.
DR ExpressionAtlas; D3Z4A5; baseline and differential.
DR GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR CDD; cd12102; DD_RIbeta_PKA; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR InterPro; IPR042818; RIbeta_DD.
DR Pfam; PF02197; RIIa; 1.
DR SMART; SM00394; RIIa; 1.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:D3Z4A5,
KW ECO:0007829|PeptideAtlas:D3Z4A5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 25..62
FT /note="RIIa"
FT /evidence="ECO:0000259|SMART:SM00394"
FT REGION 62..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 107
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122693.2"
SQ SEQUENCE 107 AA; 12333 MW; 35C8146CBE61D152 CRC64;
MASPSCFHSE DEDSLKGCEM YVQKHGIQQV LKECIVHLCV AKPDRPLRFL REHFEKLEKE
ENRQILARQK SNSQCDSHDE EISPTPPNPV VKARRRRGGV SAEVYTE
//
