ID D3Z6F1_MOUSE Unreviewed; 226 AA.
AC D3Z6F1;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 4 {ECO:0000256|ARBA:ARBA00017993};
DE Flags: Fragment;
GN Name=Arl6ip4 {ECO:0000313|Ensembl:ENSMUSP00000122377.2,
GN ECO:0000313|MGI:MGI:1929500};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122377.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122377.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122377.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000122377.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122377.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ARL6IP4 family.
CC {ECO:0000256|ARBA:ARBA00006852}.
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DR AlphaFoldDB; D3Z6F1; -.
DR jPOST; D3Z6F1; -.
DR ProteomicsDB; 373272; -.
DR Antibodypedia; 31741; 107 antibodies from 23 providers.
DR Ensembl; ENSMUST00000145667.2; ENSMUSP00000122377.2; ENSMUSG00000029404.16.
DR AGR; MGI:1929500; -.
DR MGI; MGI:1929500; Arl6ip4.
DR VEuPathDB; HostDB:ENSMUSG00000029404; -.
DR GeneTree; ENSGT00390000009670; -.
DR HOGENOM; CLU_055563_1_0_1; -.
DR ChiTaRS; Arl6ip4; mouse.
DR Proteomes; UP000000589; Chromosome 5.
DR Bgee; ENSMUSG00000029404; Expressed in floor plate of midbrain and 271 other cell types or tissues.
DR ExpressionAtlas; D3Z6F1; baseline and differential.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR019532; Nucl_RNA-splicing_assoc_SR-25.
DR Pfam; PF10500; SR-25; 1.
PE 1: Evidence at protein level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|EPD:D3Z6F1,
KW ECO:0007829|MaxQB:D3Z6F1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT REGION 8..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..117
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 226
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122377.2"
SQ SEQUENCE 226 AA; 25295 MW; 549BB238F9BDCEAC CRC64;
MLWVFEVERG QDPARHIVTS RTQKKVPDVL LESPLGGSLP LEQGTKALPS PCITERSKHK
AQRTSRSSST SSSSSSSSSA SSSSSSDGRK KRAKHKEKKR KKKKKKRKKK LKKRVKEKAV
AVHQAEALPG PSLDQWHRSA GEDNDGPVLT DEQKSRIQAM KPMTKEEWDA RQSVIRKVVD
PETGRTRLIK GDGEVLEEIV TKERHREINK QATRGDGLAF QMRTGL
//
