ID D3Z6S5_MOUSE Unreviewed; 149 AA.
AC D3Z6S5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Pleckstrin homology domain containing, family B (evectins) member 1 {ECO:0000313|Ensembl:ENSMUSP00000122333.3};
DE Flags: Fragment;
GN Name=Plekhb1 {ECO:0000313|Ensembl:ENSMUSP00000122333.3,
GN ECO:0000313|MGI:MGI:1351469};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122333.3, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122333.3, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122333.3,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000122333.3}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122333.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z6S5; -.
DR SMR; D3Z6S5; -.
DR PeptideAtlas; D3Z6S5; -.
DR ProteomicsDB; 314065; -.
DR Antibodypedia; 30966; 50 antibodies from 23 providers.
DR Ensembl; ENSMUST00000139708.9; ENSMUSP00000122333.3; ENSMUSG00000030701.18.
DR AGR; MGI:1351469; -.
DR MGI; MGI:1351469; Plekhb1.
DR VEuPathDB; HostDB:ENSMUSG00000030701; -.
DR GeneTree; ENSGT00390000013989; -.
DR ChiTaRS; Plekhb1; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000030701; Expressed in vestibular membrane of cochlear duct and 218 other cell types or tissues.
DR ExpressionAtlas; D3Z6S5; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd13265; PH_evt; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039680; PLEKHB1/2.
DR PANTHER; PTHR14309; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR14309:SF7; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:D3Z6S5,
KW ECO:0007829|PeptideAtlas:D3Z6S5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 2..109
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT NON_TER 149
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122333.3"
SQ SEQUENCE 149 AA; 17232 MW; 14031E23EED528E1 CRC64;
MALVRGGWLW RQSSILRRWK RNWFALWLDG TLGYYHDETA QDEEDRVVIH FNVRDIKVGQ
ECQDVQPPEG RSRDGLLTVN LREGSRLHLC AETRDDAIAW KTALMEANST PVRVYSPYQD
YYEVVPPNAH EATYVRSYYG PPYAGPGVT
//
