ID D3Z7C2_MOUSE Unreviewed; 68 AA.
AC D3Z7C2;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Transcription initiation factor IIA gamma chain {ECO:0000256|ARBA:ARBA00029898};
GN Name=Gtf2a2 {ECO:0000313|Ensembl:ENSMUSP00000113061.2,
GN ECO:0000313|MGI:MGI:1933289};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000113061.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000113061.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000113061.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000113061.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000113061.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001269013.1; NM_001282084.1.
DR AlphaFoldDB; D3Z7C2; -.
DR SMR; D3Z7C2; -.
DR MaxQB; D3Z7C2; -.
DR PeptideAtlas; D3Z7C2; -.
DR ProteomicsDB; 340914; -.
DR Antibodypedia; 25406; 129 antibodies from 21 providers.
DR Ensembl; ENSMUST00000119905.8; ENSMUSP00000113061.2; ENSMUSG00000033543.18.
DR GeneID; 235459; -.
DR UCSC; uc033jld.1; mouse.
DR AGR; MGI:1933289; -.
DR CTD; 2958; -.
DR MGI; MGI:1933289; Gtf2a2.
DR VEuPathDB; HostDB:ENSMUSG00000033543; -.
DR GeneTree; ENSGT00390000014572; -.
DR OrthoDB; 5052738at2759; -.
DR BioGRID-ORCS; 235459; 24 hits in 72 CRISPR screens.
DR ChiTaRS; Gtf2a2; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000033543; Expressed in atrioventricular valve and 251 other cell types or tissues.
DR ExpressionAtlas; D3Z7C2; baseline and differential.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd10145; TFIIA_gamma_N; 1.
DR Gene3D; 1.10.287.190; Transcription factor IIA gamma subunit, alpha-helical domain; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR PANTHER; PTHR10966:SF0; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D3Z7C2,
KW ECO:0007829|MaxQB:D3Z7C2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 3..48
FT /note="Transcription initiation factor IIA gamma subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02268"
SQ SEQUENCE 68 AA; 7900 MW; 306C0C6DAFB1ADB6 CRC64;
MAYQLYRNTT LGNSLQESLD ELIQSQQITP QLALQVLLQF DKAINSALAQ RVRNRVNFRI
LARILRNE
//
