ID D3ZQH1_RAT Unreviewed; 648 AA.
AC D3ZQH1;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Serine/arginine repetitive matrix 3 {ECO:0000313|Ensembl:ENSRNOP00000001957.7};
GN Name=Srrm3 {ECO:0000313|Ensembl:ENSRNOP00000001957.7,
GN ECO:0000313|RGD:1587868};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000001957.7, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000001957.7, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000001957.7,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000001957.7}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000001957.7};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3ZQH1; -.
DR STRING; 10116.ENSRNOP00000001957; -.
DR iPTMnet; D3ZQH1; -.
DR PhosphoSitePlus; D3ZQH1; -.
DR jPOST; D3ZQH1; -.
DR PaxDb; 10116-ENSRNOP00000001957; -.
DR Ensembl; ENSRNOT00000001957.8; ENSRNOP00000001957.7; ENSRNOG00000001439.8.
DR AGR; RGD:1587868; -.
DR RGD; 1587868; Srrm3.
DR VEuPathDB; HostDB:ENSRNOG00000001439; -.
DR eggNOG; KOG1869; Eukaryota.
DR GeneTree; ENSGT00940000162625; -.
DR HOGENOM; CLU_027803_0_0_1; -.
DR InParanoid; D3ZQH1; -.
DR OMA; HYQPDEY; -.
DR OrthoDB; 5324266at2759; -.
DR TreeFam; TF335721; -.
DR Proteomes; UP000002494; Chromosome 12.
DR Bgee; ENSRNOG00000001439; Expressed in cerebellum and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR CDD; cd21376; cwf21_SRRM3; 1.
DR Gene3D; 6.10.140.420; -; 1.
DR InterPro; IPR013170; mRNA_splic_Cwf21_dom.
DR InterPro; IPR047489; SRRM3_cwf21.
DR InterPro; IPR029360; SRRM_C.
DR PANTHER; PTHR34755; SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED; 1.
DR PANTHER; PTHR34755:SF2; SERINE_ARGININE REPETITIVE MATRIX PROTEIN 3; 1.
DR Pfam; PF08312; cwf21; 1.
DR Pfam; PF15230; SRRM_C; 1.
DR SMART; SM01115; cwf21; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT DOMAIN 55..100
FT /note="CWF21"
FT /evidence="ECO:0000259|SMART:SM01115"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..185
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..239
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..412
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..574
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 70923 MW; 537E983219CB7C09 CRC64;
MSSTVNNGAT SMPAPPDAAN GFPQPGGSSG SWPRAEEELR AAEPGLVKRA HREILDHERK
RRVELKCMEL QEMMEEQGYS EEEIRQKVGT FRQMLMEKEG VLTKEDRPGA HIVAETPRRM
EGLEPGLEYP PFDEDDGPVD CDCPVACYRG HRGYRTKHWS SSSASPPPKK KKKKKGSHRR
SRKKRRLESE CSCGSASPLR KKKRSVKKHR RDRSDSGSRR KRRYRSRSLK SKRKEKIKER
KRPHTESPGR RSHHHSSVSS HSPSVSSHYS DSGSPNRLSP KHRDDGRKTG SQRSSGSRSL
SPSGGSGWGS PQQNGGSRQR SGAHGGRPGS AHSPPDKPSS PRACDKAAAA PTPPARGKDS
QSPRSAPSSQ GRGGRAAGGT ARRRRRRRRR RRSRSSANAP RRRGRRRAKP APPRGSSRSL
SGAHSSSDSG GGAPGPGPEP GSERGHGGHG KRAKERPPRA RPASTSPSPG AHGRRGGPEG
NSSSRSPGPH PGSWSSSRSP SKSRSRSPDK RTRSPSLSPS PKKPLGRDKD SEGRARHAEA
EAARTRRRSR SYSPIRKRRR DSPSFMEPRR ITSARKRPIP YYRPSPSSSS SCLSSDYSSR
SRSRSPSPGH SHGSYSSRSH GTRSRSCSAS RSRSPSYHSR SSSESGGF
//
