ID D4A0C3_RAT Unreviewed; 787 AA.
AC D4A0C3;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=HID1 domain containing {ECO:0000313|Ensembl:ENSRNOP00000004718.5};
GN Name=Hid1 {ECO:0000313|Ensembl:ENSRNOP00000004718.5,
GN ECO:0000313|RGD:1311422};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000004718.5, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000004718.5, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000004718.5,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0007829|PubMed:22673903}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
RN [3] {ECO:0000313|Ensembl:ENSRNOP00000004718.5}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000004718.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001291219.1; NM_001304290.1.
DR AlphaFoldDB; D4A0C3; -.
DR STRING; 10116.ENSRNOP00000004718; -.
DR PhosphoSitePlus; D4A0C3; -.
DR jPOST; D4A0C3; -.
DR PaxDb; 10116-ENSRNOP00000004718; -.
DR PeptideAtlas; D4A0C3; -.
DR Ensembl; ENSRNOT00000004718.7; ENSRNOP00000004718.5; ENSRNOG00000003464.7.
DR GeneID; 287822; -.
DR KEGG; rno:287822; -.
DR AGR; RGD:1311422; -.
DR CTD; 283987; -.
DR RGD; 1311422; Hid1.
DR VEuPathDB; HostDB:ENSRNOG00000003464; -.
DR eggNOG; KOG2226; Eukaryota.
DR GeneTree; ENSGT00390000003070; -.
DR HOGENOM; CLU_007392_1_0_1; -.
DR InParanoid; D4A0C3; -.
DR OMA; IFEDDKW; -.
DR TreeFam; TF314291; -.
DR Proteomes; UP000002494; Chromosome 10.
DR Bgee; ENSRNOG00000003464; Expressed in pancreas and 19 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR GO; GO:0005881; C:cytoplasmic microtubule; ISO:RGD.
DR GO; GO:0098548; C:cytoplasmic side of Golgi membrane; ISO:RGD.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005797; C:Golgi medial cisterna; ISO:RGD.
DR GO; GO:0000138; C:Golgi trans cisterna; ISO:RGD.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR026705; Hid-1/Ecm30.
DR PANTHER; PTHR21575; PROTEIN HID1; 1.
DR PANTHER; PTHR21575:SF12; PROTEIN HID1; 1.
DR Pfam; PF12722; Hid1; 1.
PE 1: Evidence at protein level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT REGION 570..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 787 AA; 88626 MW; 7E8E7EEC74CC5B51 CRC64;
MGSADSKLNF RKAVIQLTTK TQPVEATDNA FWDQFWADTA TSVQDVFALV PAAEIRAVRE
ESPSNLATLC YKAVEKLVQG AEGGCHSEKE KQVVLNCSRL LTRVLPYIFE DPDWRGFFWS
TVPGAGRGGG EEEDENARPL AESLLLAIAD LLFCPDFTVQ NHRRNDVDSA EDVHSLDSCE
YIWEAGVGFA HSPQPNYIHD MNRMELLKLL LTCFSEAMYL PPSPESGSTN PWVQFFCSTE
NRHALPLFTS LLNTVCAYDP VGYGIPYNHL LFSDYREPLV EEAAQVLIVT LDHDSATSTS
PTVDGTTTGT VMDDADPPGP ENLFVNYLSR IHREEDFQFI LKGIARLLSN PLLQTYLPNS
TKKIQFHQEL LVLFWKLCDF NKKFLFFVLK SSDVLDILVP ILYFLNDARA DQSRVGLMHI
GVFILLLLSG ERNFGVRLNK PYSVRVPMDI PVFTGTHADL LIVVFHKIIT SGHQRLQPLF
DCLLTIVVNV SPYLKSLSMV TANKLLHLLE AFSTTWFLFS ASQNHHLVFF LLEVFNNIIQ
YQFDGNSNLV YAIIRKRGVF HQLANLPTDP PSIHKALQRR RRTPEPLSRA GSQEGASMEG
SRPAAPAEPG TLKTSLVATP GIDKLTEKSQ VSEDGTLRSL EPESQQNSAE GSPSEGEPNQ
TWREQRRLSN ASASGQWSPT SDWILSWKSK LPLQTIMRLL QVLVPQVEKI CIDKGLTDES
EILRFLQHGT LVGLLPVPHP ILIRKYQANS GTAMWFRTYM WGVIYLRNVD PPIWYDTDVK
LFEIQRV
//
