ID   D4CGP2_9CLOT            Unreviewed;      1423 AA.
AC   D4CGP2;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:EFE11143.1};
GN   ORFNames=CLOM621_08616 {ECO:0000313|EMBL:EFE11143.1};
OS   Clostridium sp. M62/1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=411486 {ECO:0000313|EMBL:EFE11143.1, ECO:0000313|Proteomes:UP000004936};
RN   [1] {ECO:0000313|EMBL:EFE11143.1, ECO:0000313|Proteomes:UP000004936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M62/1 {ECO:0000313|EMBL:EFE11143.1,
RC   ECO:0000313|Proteomes:UP000004936};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFE11143.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACFX02000043; EFE11143.1; -; Genomic_DNA.
DR   RefSeq; WP_008398977.1; NZ_GG730316.1.
DR   HOGENOM; CLU_002393_1_0_9; -.
DR   OrthoDB; 9802715at2; -.
DR   Proteomes; UP000004936; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT   DOMAIN          7..255
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          321..575
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          670..890
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1423 AA;  157310 MW;  22BE32A674324901 CRC64;
     MKSCKRLGID IGSTTVKVAI IDDDNRILFA DYERHFANIQ ETLALLLSRA VEVLGDMELY
     PMITGSGGLT LSSHLEVPFV QEVVSVASAL QDYAPQTDVA IELGGEDAKI IYFTGGIDQR
     MNGICAGGTG SFIDQMAALL QTDASGLNEY AKNYKAIYPI AARCGVFAKS DIQPLINEGA
     TREDLAASIF QAVVNQTISG LACGKPIRGT VAFLGGPLHF LSELRAAFIR TLNLGPDRIV
     APDHSHLFAA VGAAMNSKCE VSMNASSMIE RLKKGIKMDF EVNRMEPLFE NEAAYEEFKT
     RHENHCVKKG DLSTYKGNCF LGIDAGSTTT KVALVGEDGT LLYNFYSSNN GSPLATAIRA
     MKEIDEKLPE GAHIVYSCST GYGEALLKAA FMLDEGEVET ISHYYAAAFF EPDVDCILDI
     GGQDMKCIKI KDGTVDSVQL NEACSSGCGS FIETFAKSLN YSVIDFAKEA LFAKNPTDLG
     TRCTVFMNSN VKQAQKEGAS VADISAGLAY SVIKNALFKV IKITNASDLG KHVVVQGGTF
     YNDAVLRSFE KIAGCEAVRP DIAGIMGAFG AALIARERYD ASRETSMLPM EKILNLSYKT
     SMTRCQGCTN HCVLTINRFD GGRQFVTGNR CERGLGHSKK KEDIPNLFDY KFHRMFDYEP
     LTADVAKRGT VGIPRVLNLY ENYPFWAVFF KKLGFRTVLS PQSTRKIYEL GIESIPSESE
     CYPAKLAHGH VEWLIKQGVK YIFYPCIPYE RNEMPEAGNH YNCPMVTSYA ENIKNNVEEL
     HGNEILFRNP FMAFTNEEIL TDALVKEFTE QFQIPEKEIR EAAGEAWKEL LASRKDMEKK
     GEEVLRWLVD NNRHGIVLAG RPYHVDPEIN HGIPELITSY GFAVLTEDSV SHLGNVERPL
     IVTDQWMYHS RLYAAANFVK TQENLDLIQL NSFGCGLDAV TTDQVNDILT HSGKIYTCLK
     IDEVNNLGAA RIRIRSLISA IRVRERKHYQ HDVVTSAYSR VFFTKEMKKD YTILCPQMSP
     IHFDLIEPAV RSCGYKLEVL QNSDRTAIDT GLKFVNNDAC YPSLIVVGQI MSALLSGKYD
     LNRTAIIMSQ TGGGCRASNY IGFIRRALER AGMPQIPVIS LNANGMETNP GFSFTLPMVI
     KALQAVVYGD VFMRVLYATR PYEAKPGSAD ALHEQWKERC IASLTKKKPS MKEFSRNLRG
     IISDFDTLAR RNVVKPKVGI VGEILVKFSP LANNHVVDLL ESEGAEAVMP DLLDFLLYCF
     YNSNFKAENL GGKKSTAWLC NVGIQMLEYF RRTARKELEK STHFIPPARI HDLAAMAKSY
     VSLGNQTGEG WFLTGEMLEL IHSGTKNIIC TQPFGCLPNH IVGKGVIKEL RASHPEANII
     AVDYDPGASE VNQLNRIKLM LATAQKNLNA EAAAEAAAAG ERA
//