ID D4D132_TRIVH Unreviewed; 783 AA.
AC D4D132;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 13-SEP-2023, entry version 45.
DE RecName: Full=CorA family metal ion transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRV_00779 {ECO:0000313|EMBL:EFE44430.1};
OS Trichophyton verrucosum (strain HKI 0517).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663202 {ECO:0000313|EMBL:EFE44430.1, ECO:0000313|Proteomes:UP000008383};
RN [1] {ECO:0000313|Proteomes:UP000008383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HKI 0517 {ECO:0000313|Proteomes:UP000008383};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE44430.1}.
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DR EMBL; ACYE01000049; EFE44430.1; -; Genomic_DNA.
DR RefSeq; XP_003025041.1; XM_003024995.1.
DR AlphaFoldDB; D4D132; -.
DR GeneID; 9580533; -.
DR KEGG; tve:TRV_00779; -.
DR HOGENOM; CLU_007127_10_0_1; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000008383; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REGION 1..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..30
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 88355 MW; 5F55347CB4BA760D CRC64;
MDPTTSVMGA ERSAPKKRRH RAPRKKRNRR PSFAPAGDNS HFQSPLSRVD TQPNEEHEDT
KDASLTETRP RPFYNLGRSG GGNLSETSLE SEALLDHRHE TLPEDDFAIT DDRSPLLNSS
AQNGGALRGY GSDLRSPYSM PAGMGSPTSR RSPQNSYTPD AFLASRQGYD VNNPPSMPGS
PKIMPNNMGY DETVITGPEF VRQQSPEALS CHSLPMDAVV NVDTDSRRPG LQSRHGSMSR
SPADLQRRRT LTLPVEEDVC FPASGLSDLG EEDLQSHIPT GGDTRERRRR SRRVWPDLSV
LDEWSQHEKE ARSGGTRSKR IDEPVLIGGR LRTRNLAWKQ DEEEEAPYRF TYFNEDFQST
LHSQTLSELE QPGQTFRDLF IPEPPLLEDD SSDEEDDSPP HSGTTSRDKH PSISTNANHN
TNNLPDLLSD NPNSTSPQPT NGNSRIPSPK KEPRYGPRPT FWLDVLSPTD SEMRIIAKAF
GIHALTAEDI MMQEAREKVE LFRNYYFINY RTFEQDVNSP DFLEPVNMYV VVFREGLLSF
HFSRTPHPAN VRRRIRQLKD YLILSADWIS YAIIDDITDV FGPLIHAIEE EVDEIDDKIL
RLHSDDKEMG SDQNNEKTAA LEESGSGTNM LRQVGACRKK VMGLYRLLGN KADVIKGFAK
RCNEYWEVAP KSEIGLYLGD IQDHILTMTS NLTHYETLLS RVHSNYLAQI NIRMNERQEQ
TADVLGKLTV LGTIVLPMNI ICGMWGMNVK VPGQDVESLN WFWSSMFPEH LILVHQSPIG
AGC
//
