ID D4DG43_TRIVH Unreviewed; 218 AA.
AC D4DG43;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Protein YAE1 {ECO:0000256|ARBA:ARBA00018400};
DE AltName: Full=Protein yae1 {ECO:0000256|ARBA:ARBA00017286};
GN ORFNames=TRV_06145 {ECO:0000313|EMBL:EFE39176.1};
OS Trichophyton verrucosum (strain HKI 0517).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663202 {ECO:0000313|EMBL:EFE39176.1, ECO:0000313|Proteomes:UP000008383};
RN [1] {ECO:0000313|Proteomes:UP000008383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HKI 0517 {ECO:0000313|Proteomes:UP000008383};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC protein assembly (CIA) complex machinery. May be required for
CC biogenesis of the large ribosomal subunit and initiation of
CC translation. {ECO:0000256|ARBA:ARBA00003836}.
CC -!- SUBUNIT: May form a complex with LTO1. {ECO:0000256|ARBA:ARBA00011427}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the YAE1 family.
CC {ECO:0000256|ARBA:ARBA00007096}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE39176.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACYE01000346; EFE39176.1; -; Genomic_DNA.
DR RefSeq; XP_003019800.1; XM_003019754.1.
DR AlphaFoldDB; D4DG43; -.
DR GeneID; 9584551; -.
DR KEGG; tve:TRV_06145; -.
DR HOGENOM; CLU_066684_1_0_1; -.
DR OrthoDB; 2018411at2759; -.
DR Proteomes; UP000008383; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR019191; Essential_protein_Yae1_N.
DR InterPro; IPR038881; Yae1-like.
DR PANTHER; PTHR18829; PROTEIN YAE1 HOMOLOG; 1.
DR PANTHER; PTHR18829:SF0; PROTEIN YAE1 HOMOLOG; 1.
DR Pfam; PF09811; Yae1_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 78..116
FT /note="Essential protein Yae1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09811"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 23012 MW; 332BC3A8E2E21036 CRC64;
MSSPSPGEEA GRLTDMASNG LDDIFGSSPP RTAAETTAAS AADEDGDMLG SRAGENTVPS
LAESSDLPSL RRQHVTAGYR DGVTAAKGEH VQRGFDKGYP VGAELGVRVG IVLGVLEGLV
KALSSGGGGG EEEEKAEDKD SRAASRARVT ALFETAKREL VLERIFSLEE QGTVKEVERG
EEGEGEDHGD PYSRLGQAGD TAVTRWEDRV RILLAELR
//
