ID D4DXX2_SEROD Unreviewed; 796 AA.
AC D4DXX2;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
DE AltName: Full=Beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00030512};
DE AltName: Full=N-acetyl-beta-glucosaminidase {ECO:0000256|ARBA:ARBA00033000};
GN ORFNames=HMPREF0758_0755 {ECO:0000313|EMBL:EFE97464.1};
OS Serratia odorifera DSM 4582.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=667129 {ECO:0000313|EMBL:EFE97464.1, ECO:0000313|Proteomes:UP000005723};
RN [1] {ECO:0000313|EMBL:EFE97464.1, ECO:0000313|Proteomes:UP000005723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4582 {ECO:0000313|EMBL:EFE97464.1,
RC ECO:0000313|Proteomes:UP000005723};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE97464.1}.
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DR EMBL; ADBY01000017; EFE97464.1; -; Genomic_DNA.
DR RefSeq; WP_004955827.1; NZ_GG753567.1.
DR AlphaFoldDB; D4DXX2; -.
DR STRING; 667129.HMPREF0758_0755; -.
DR HOGENOM; CLU_007082_5_1_6; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000005723; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 2.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFE97464.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005723};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..796
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003055849"
FT DOMAIN 29..157
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 161..416
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 544..586
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 317
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 796 AA; 89108 MW; D8DD9DE52E4FC676 CRC64;
MHKIHRYTLP ALSLLLSLNA LAQPAGELPL MPWPQQVTLS QPPGKWLLNQ RLAIRVQGDD
LDEAVTRWRQ RIEMQTGWQL APATSPDAAI IEVRVKHAVA AQPLPDSDES YQLSVTPQGA
TLIANTRFGA LRGMETLLQL VQTDADGTFL PLVSVTDVPR FPWRGVLLDS ARHFLPVADI
LRQLDGMAAA KLNVFHWHLT DDQGWRFAST RYPKLQQLAS DGQFYTREQM QQVVAYAAAR
GIRVVPEIDL PGHASSIAVA YPQLISAPGP YQMQREWGVH RPTLDPSNKQ VYVFIEAIIG
ELAEIFPDPY LHIGGDEVDA SQWQQSSAVQ ALMKQQQLAD THALQAWFNQ RLEQILERHQ
RRMVGWDEIY HPSLPRTIVI QSWQGPDSLG ASAQDGYQGI LSTGFYLDQP QSTAYHYRNE
ILPQPLGVDS AVGEGERAQS WQFSMPRLKG SPVEGSFTLI EGANGWRGFI DFNGKSRRAL
QDIVWLAPGR LTFRVDSWMG ETRPVLSLQQ QTLSGYIRVG NVRYPTSGSR LAVMPQGKMP
VVPDPRQQAN ILGGEAALWA ENVRAPLIDL KLWPRAFAVA ERLWSAQDVS DENNMYRRLA
TVDAWSVVSV GLQQHAQTAR EFTRLANSVD IMPLQIFAEA LEPAQYYTRQ HLKFQAGNYH
QFEPLNRLAD ALPAESSAVR DMTLQVAALL KDRDNRVAQA ALRERLQRWQ QNGAALQPMV
AGNQLMLELA PVAQDVETLA DIGLMLLDRW QQGKPLNGSE AQQVQRQLDA AAQVRDELVI
AAVYPLETLL HALTVR
//
