ID D4GR47_HALVD Unreviewed; 681 AA.
AC D4GR47;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=N-methylhydantoinase (ATP-hydrolyzing) A {ECO:0000313|EMBL:ADE01771.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:ADE01771.1};
GN Name=hyuA2 {ECO:0000313|EMBL:ADE01771.1};
GN OrderedLocusNames=HVO_A0379 {ECO:0000313|EMBL:ADE01771.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV4 {ECO:0000313|EMBL:ADE01771.1,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE01771.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE01771.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001955; ADE01771.1; -; Genomic_DNA.
DR RefSeq; WP_013035057.1; NC_013966.1.
DR AlphaFoldDB; D4GR47; -.
DR PaxDb; 309800-C498_10466; -.
DR EnsemblBacteria; ADE01771; ADE01771; HVO_A0379.
DR GeneID; 8923298; -.
DR KEGG; hvo:HVO_A0379; -.
DR eggNOG; arCOG01511; Archaea.
DR HOGENOM; CLU_002157_1_2_2; -.
DR OrthoDB; 8261at2157; -.
DR Proteomes; UP000008243; Plasmid pHV4.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ADE01771.1};
KW Plasmid {ECO:0000313|EMBL:ADE01771.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243}.
FT DOMAIN 8..184
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 206..491
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 504..672
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
SQ SEQUENCE 681 AA; 72968 MW; 69AC5299BF61C6C3 CRC64;
MSQDNTQRVA VDIGGTFVDA ITFDRETRDI ALEKAATTPN QPSEGVIESV NGVDADLESA
NAFVHGTTLG LNAVLERDGA RTGIITNEGF ADVYEIGRTN LERTAMYDIN YEKPESIVPR
RRRVGVPGRL DADGAVVEEI DTDAVAEAAE YLVEKQDVDS IAICFLHAYQ NGQHEQAAAE
CVQDAYPDIS VSVSSDISGE YREYERTSTA VLDGYIKPIF ENYVDTLDAS LRDGGFDGSF
FVTRSGGGTL TAESAKSAPA HTILSGPAGG LIGASHVGRV TDRDNLITVD MGGTSLDAAV
VEDGSPVVKY DSSLEHQPLM IPVYDIRTIG AGGGSIAWID GDLLKVGPES AGADPGPICY
DNGGTQPTVT DAALALGFLD PGDFLGGDMD TAAGDALDGI EEELAEPLGM TVDEASKGVL
DVALANTVGA IREITVEKGL DPRDFSMVAY GGAGPMFVPL LARELGASEV LVPQAPSVFS
AWGMLMADVV YDFSQTHLAV LDDATLNELK TAFADLEAEG RETLTAEGVA ENRQRIGRAV
EMRYFGQEHT VEVDADGVSS LDELAERFED QHETRYGHTM DDPVQVVHLR VRAVGENDKP
ELERGTPRED SELTPADTRE AYCFAEDDFV EFDVYRRDDL KPGDEIRGPA VVTEPTTSLV
FHSDQTATTD DYGHIIITTD Q
//
