ID D4H5P9_DENA2 Unreviewed; 595 AA.
AC D4H5P9;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Cl-channel voltage-gated family protein {ECO:0000313|EMBL:ADD69490.1};
GN OrderedLocusNames=Dacet_2736 {ECO:0000313|EMBL:ADD69490.1};
OS Denitrovibrio acetiphilus (strain DSM 12809 / NBRC 114555 / N2460).
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Geovibrionaceae; Denitrovibrio.
OX NCBI_TaxID=522772 {ECO:0000313|EMBL:ADD69490.1, ECO:0000313|Proteomes:UP000002012};
RN [1] {ECO:0000313|EMBL:ADD69490.1, ECO:0000313|Proteomes:UP000002012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12809 / NBRC 114555 / N2460
RC {ECO:0000313|Proteomes:UP000002012};
RX PubMed=21304711; DOI=10.4056/sigs.892105;
RA Kiss H., Lang E., Lapidus A., Copeland A., Nolan M., Glavina Del Rio T.,
RA Chen F., Lucas S., Tice H., Cheng J.F., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brettin T.,
RA Spring S., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Denitrovibrio acetiphilus type strain
RT (N2460).";
RL Stand. Genomic Sci. 2:270-279(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001968; ADD69490.1; -; Genomic_DNA.
DR RefSeq; WP_013011983.1; NC_013943.1.
DR AlphaFoldDB; D4H5P9; -.
DR STRING; 522772.Dacet_2736; -.
DR PaxDb; 522772-Dacet_2736; -.
DR KEGG; dap:Dacet_2736; -.
DR eggNOG; COG0038; Bacteria.
DR eggNOG; COG0517; Bacteria.
DR HOGENOM; CLU_015263_5_3_0; -.
DR InParanoid; D4H5P9; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000002012; Chromosome.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002012};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 461..519
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 526..588
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 595 AA; 64694 MW; 0DA0EB4A3E0B100A CRC64;
MFTGKRFNLP VIGRWFILGS IVGLVSGVGA IIFFLLLQGS SFFFMDYLMG IRVEETGGEH
ALFGHAATEF RRWSILLVPA LGGLISGFLV YKFAPEAEGH GTDAAIKAIH FKNGSIRWRV
PIIKTFASAI TIGTGGSGGR EGPIAQIGAG FGSFLGTTLK LSERERRILT AAGMGAGVGA
IFRSPLAGAI FAAEVLYASS DMEYEALLPS AITSIIAYSV FCSVYGWEPL FATPDFAFEN
PVELIGYSVL GFACAVFGWL YVRTFYGIHG IFKQMHISPY IKPVIGGFLT GCVGFFVPQA
LAGSYAQIEL GMQGQLGIGF IFILIFAKIL TTSFSIGSGG SAGIFGPSMV IGAAVGGFVG
LALNSFVPFI APEPGAYVIV GMAGFFSGIA NTPLSTIIMV SEMTGNYHLL VPSMWVSTLA
FLLLRKTTMY VNQVPMRSES PIHKGEFFVQ VLQDIKVADV MRPDPIILKE DMHFYDILHF
IPQTKHNNFP VVKEDGTLVG VLLFEEIREF VFEEGLEDLV VAEEVCETDV PTIRPSNSLA
DAIENIGFKN IELLPVVDEE TQTKLVGIIT RRDIISTYNK VLRKRRSEKV EESEF
//
