ID D4IIN6_9BACT Unreviewed; 694 AA.
AC D4IIN6;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Subtilisin-like serine proteases {ECO:0000313|EMBL:CBK62794.1};
GN ORFNames=AL1_00630 {ECO:0000313|EMBL:CBK62794.1};
OS Alistipes shahii WAL 8301.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=717959 {ECO:0000313|EMBL:CBK62794.1, ECO:0000313|Proteomes:UP000008794};
RN [1] {ECO:0000313|EMBL:CBK62794.1, ECO:0000313|Proteomes:UP000008794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL 8301 {ECO:0000313|EMBL:CBK62794.1,
RC ECO:0000313|Proteomes:UP000008794};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J.;
RT "The genome sequence of Alistipes shahii WAL 8301.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK62794.1, ECO:0000313|Proteomes:UP000008794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL 8301 {ECO:0000313|EMBL:CBK62794.1,
RC ECO:0000313|Proteomes:UP000008794};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; FP929032; CBK62794.1; -; Genomic_DNA.
DR RefSeq; WP_015545748.1; NZ_CP102253.1.
DR AlphaFoldDB; D4IIN6; -.
DR STRING; 717959.AL1_00630; -.
DR MEROPS; S08.154; -.
DR KEGG; ash:AL1_00630; -.
DR PATRIC; fig|717959.3.peg.2115; -.
DR HOGENOM; CLU_014786_0_0_10; -.
DR OrthoDB; 1489355at2; -.
DR BioCyc; ASHA717959:AL1_RS00260-MONOMER; -.
DR Proteomes; UP000008794; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR032304; Peptidase_S8_N.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16361; Peptidase_S8_N; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000008794};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..694
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003059227"
FT DOMAIN 46..196
FT /note="Subtilase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16361"
FT DOMAIN 226..554
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 234
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 286
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 517
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 694 AA; 73799 MW; 26C3B0BCBEBDA661 CRC64;
MKKLLLLCGL LAVFACTEEP ADSAGGNGGR KARVLGSPTS RLALRGSLSV KLSPETAQAV
AAAQAQLPAT RSGVATRSGV GGIDAILHEI DAGRFERVVA YNPEWEDVYE QTGINRWYTI
AFDDEIQLSE VGERLAALPG VAVVEYGIDP RYIRPMSEGP AVPASEGMFP RVGETRAAKA
MNDPMLPFQW NYDNPGGGLF PDVAVKPEAG ADIDLLDAWQ LCTGSEEVIV AVIDEPVQIT
HPDLRANIWS NPKNSQEHGY NFWDDTPELD WKSVGGDDRN PEYADHGTHV AGVIAAVNNN
GRGVCGIAGG RSNSGGVRIM SCQIMGNSTT GGKGNPTVKA FEYAWTNGAI IAQNSWGYNL
ETADGTKITP EEFEREWKSN YGIMRDAIDT FVRGAGTRNP NSPLQGGLVI FAAGNEGDVY
GDVRIYPAAY DPVIAVGAMD WSFRPAYYTD YGPWVDIAAP GGDRYSGKTT RTASDGRTVF
YSNAQILSTI LCDDAIAYQD GRKDGGMYGY GFMQGTSMAC PHVSGVAALG LAYAAQNGKK
YTPAEFKALL LSSVYGIDDC FTGSKDGELG PIADMAVYKN KMGGGCIDAL KLLFAVKGTP
AVYVRTGEPV TVDFARYFGG DRSRVALTAA SFASPGNLGL SSSKAVFDGT KITFDCPEPG
TSMLRISAVS GDTEFVREFA VVSRAGLAAN GGWL
//
