ID D4ILW5_9BACT Unreviewed; 611 AA.
AC D4ILW5;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily {ECO:0000313|EMBL:CBK63927.1};
GN ORFNames=AL1_14970 {ECO:0000313|EMBL:CBK63927.1};
OS Alistipes shahii WAL 8301.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=717959 {ECO:0000313|EMBL:CBK63927.1, ECO:0000313|Proteomes:UP000008794};
RN [1] {ECO:0000313|EMBL:CBK63927.1, ECO:0000313|Proteomes:UP000008794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL 8301 {ECO:0000313|EMBL:CBK63927.1,
RC ECO:0000313|Proteomes:UP000008794};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J.;
RT "The genome sequence of Alistipes shahii WAL 8301.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK63927.1, ECO:0000313|Proteomes:UP000008794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL 8301 {ECO:0000313|EMBL:CBK63927.1,
RC ECO:0000313|Proteomes:UP000008794};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FP929032; CBK63927.1; -; Genomic_DNA.
DR RefSeq; WP_015546821.1; NZ_CP102253.1.
DR AlphaFoldDB; D4ILW5; -.
DR STRING; 717959.AL1_14970; -.
DR KEGG; ash:AL1_14970; -.
DR PATRIC; fig|717959.3.peg.3179; -.
DR HOGENOM; CLU_014653_3_1_10; -.
DR OrthoDB; 9777768at2; -.
DR BioCyc; ASHA717959:AL1_RS06975-MONOMER; -.
DR Proteomes; UP000008794; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008794};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:CBK63927.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..611
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003058870"
FT TRANSMEM 50..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 271..538
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 319
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 279
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 319
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 437
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 485
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 486
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 611 AA; 67753 MW; BE3ED4A54FFCB6A0 CRC64;
MRRKFAFLVT VFCATVLAMA VQKPVFMAWY AAEAAGAGFG GWMEVLWHGL TLDMTVAGYV
TALPLLAVLL SLWVRIPERV WRGVLTAYFA LIAVVTAVIF AVDVALYEHW GFRIDATVLI
YLSDPEEAMA SVDFWLGVRQ TLLAAAYAAP MLWAYCRILR IFDGRPVGWR LALPGSLVVV
VLAGFDFLAI RGGLGASVAN VSKVYFSPVP FLNHAATNPV FSFLSSLGDR ADYAGEYPFF
DEETRAAKFD ALRGNGPAAG PTERVLDTLR PNVVIVILES FARTVMDAEV DGEPVMPNMQ
RLKREGVWFE NFFANSFRTD RGEVAILSGF PAQTRMSIMK LPAKSRNLPS VARSLAGEGY
KTSFAYGGDL NFTNQASYMY ATGWQELIWQ KDLRFDAPAS DWGYDDRLMC DWFADRVIAL
SESREPFLAG LLTLSSHTPF DVPYAKFDDR VLNAMAFSDD CVGKMIDRLK ASPAWENLLV
VLVADHGYPY PRTLAYNEPL RHRIPMIWTG GAVARPRVVE DYASQIDIAA TLLAQLGVPH
DDFDYSKDIF APTPPRKFAY YAFNDGFGVV DASGEAVWDA TGGRAVTETN PELLDVGRTM
LQTTYVDIGR R
//
