ID D4JY50_9FIRM Unreviewed; 438 AA.
AC D4JY50;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=NADPH-dependent glutamate synthase beta chain and related oxidoreductases {ECO:0000313|EMBL:CBK98949.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:CBK98949.1};
DE EC=1.4.1.14 {ECO:0000313|EMBL:CBK98949.1};
GN ORFNames=FP2_14600 {ECO:0000313|EMBL:CBK98949.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK98949.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBK98949.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK98949.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FP929045; CBK98949.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JY50; -.
DR STRING; 718252.FP2_14600; -.
DR KEGG; fpr:FP2_14600; -.
DR PATRIC; fig|718252.3.peg.2817; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_3_9; -.
DR BioCyc; FPRA718252:G1375-1238-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0016040; F:glutamate synthase (NADH) activity; IEA:UniProtKB-EC.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CBK98949.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804}.
FT DOMAIN 5..99
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 112..394
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 438 AA; 47474 MW; A0A40EF4F0E91383 CRC64;
MALHVLDEAN RCLGCKKPMC QQGCPIRTNI PEVIRLLKDN HLDDAGRMLF ENNPLTTVCS
LVCNHENQCE GHCIRNRMPS HDPVHFSIIE DYISTTYANK MTSGPAPRNG MKAAVVGSGP
AGLTVAVLLA RWGYDVTIFD ARDKIGGVMR YGIPNYRLPD SVLDDFQYRH LELKGIHVRP
NTAIGKTITI DDLFRDGYKS VFIGAGLWKA NAMHIKGETL GNVAFGIDYL ANSKAFQLGD
DIAVIGVGNS AMDCARTAIR NGARHVTCYA RRDEECISAS EHEVRYAKLE GVGFRFCKAP
VEIRENGIIC RDTVKGEDGK FTQVEGSETF YPHTGVIVSV SQGSENSLVK TTTGIETNQR
GLLTVNEDGS TTREGVFAGG DAVMGARTVV EAVAIAKKVA ASMDAYMKAL PADNTPDPYA
GIPVFSTPPS DVLAKQGV
//
