ID D4K0R8_9FIRM Unreviewed; 268 AA.
AC D4K0R8;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=rRNA methylase, putative, group 3 {ECO:0000313|EMBL:CBK99867.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:CBK99867.1};
GN ORFNames=FP2_25520 {ECO:0000313|EMBL:CBK99867.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK99867.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBK99867.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK99867.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP929045; CBK99867.1; -; Genomic_DNA.
DR AlphaFoldDB; D4K0R8; -.
DR STRING; 718252.FP2_25520; -.
DR KEGG; fpr:FP2_25520; -.
DR PATRIC; fig|718252.3.peg.741; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_0_1_9; -.
DR BioCyc; FPRA718252:G1375-2182-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:CBK99867.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW Transferase {ECO:0000313|EMBL:CBK99867.1}.
FT DOMAIN 24..99
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 28255 MW; CDA39CAB3F0C435F CRC64;
MEERNMPRRP RREKADDQPR NESLVYGKNP VTELLKSGSG VDTVLLAEGM APAVAAYYTA
MAKEAGATVK RVHPNKLRLM TGTESHQGVA AFASEIEYAT VEDLLAAAKE KGEPPFLVLS
DGIEDPHNLG AVMRSALLCG AHGIVIPKRG GASVTPTVIK SSAGAAERLP VARVANIGET
IRRLKEQGVF VYCADMDGVS LRKNNLTGPI ALVLGSEGSG VSQLVKKLCD GVVSLDMTAQ
GTGVDSFNVS VAAGIILYEI QSQRAAQS
//
