ID   D4K280_9FIRM            Unreviewed;       437 AA.
AC   D4K280;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Gluconolactonase {ECO:0000313|EMBL:CBL00379.1};
GN   ORFNames=FP2_31380 {ECO:0000313|EMBL:CBL00379.1};
OS   Faecalibacterium prausnitzii L2-6.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=718252 {ECO:0000313|EMBL:CBL00379.1, ECO:0000313|Proteomes:UP000008804};
RN   [1] {ECO:0000313|EMBL:CBL00379.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBL00379.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929045; CBL00379.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4K280; -.
DR   STRING; 718252.FP2_31380; -.
DR   KEGG; fpr:FP2_31380; -.
DR   PATRIC; fig|718252.3.peg.1341; -.
DR   eggNOG; COG3386; Bacteria.
DR   HOGENOM; CLU_626637_0_0_9; -.
DR   BioCyc; FPRA718252:G1375-2708-MONOMER; -.
DR   Proteomes; UP000008804; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013658; SGL.
DR   PANTHER; PTHR10426:SF106; ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED; 1.
DR   PANTHER; PTHR10426; STRICTOSIDINE SYNTHASE-RELATED; 1.
DR   Pfam; PF08450; SGL; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          225..347
FT                   /note="SMP-30/Gluconolactonase/LRE-like region"
FT                   /evidence="ECO:0000259|Pfam:PF08450"
SQ   SEQUENCE   437 AA;  46069 MW;  57D1D2B81A4DE2BF CRC64;
     MRIGFVELVL LLFIASITVG PNAALFVDRW LRRAQRTSAA AARRKAQLEA QAAIEREALM
     TRFRVASNIF ALLMLAALAY GLLLRPIDTP PKAYTTPDVR QDTGAAQTAL SADSKDGWKP
     GGYLGVDCVR TQDGLVYAAA YNGAAMKKRQ SDLVRTDGGH TAAILSVEGE LTGFAFDADG
     DLWLTVVTPS GGALCRARHD SWGTSVEQVV TQIDGAPLGV LSAVETGPDG KVYFAVSTEA
     AAKNGLESAL RTELIAHTGT GCVYVYDPSA RTVEQVLGGV AGAAGLALSE DGRTLYVSDL
     GERCVWAVDA DARELTAGGK HCESFVSGLP GYPGALALDE DGILYISYRW TRSGWLEKHA
     DSTLLRGIAL RAGENIQKKL FKLPADAPCA EAVDTADGSW KQTFSGRELD GCTAVCPAGS
     KVYFGAAGSA SLLSARV
//