ID   D4KBB3_9FIRM            Unreviewed;      1551 AA.
AC   D4KBB3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=DNA methylase {ECO:0000313|EMBL:CBL02126.1};
GN   ORFNames=FPR_18970 {ECO:0000313|EMBL:CBL02126.1};
OS   Faecalibacterium prausnitzii SL3/3.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=657322 {ECO:0000313|EMBL:CBL02126.1, ECO:0000313|Proteomes:UP000007059};
RN   [1] {ECO:0000313|EMBL:CBL02126.1, ECO:0000313|Proteomes:UP000007059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL3/3 {ECO:0000313|EMBL:CBL02126.1,
RC   ECO:0000313|Proteomes:UP000007059};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Faecalibacterium prausnitzii SL3/3.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBL02126.1, ECO:0000313|Proteomes:UP000007059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL3/3 {ECO:0000313|EMBL:CBL02126.1,
RC   ECO:0000313|Proteomes:UP000007059};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929046; CBL02126.1; -; Genomic_DNA.
DR   KEGG; fpa:FPR_18970; -.
DR   PATRIC; fig|657322.3.peg.1812; -.
DR   eggNOG; COG0249; Bacteria.
DR   eggNOG; COG0553; Bacteria.
DR   eggNOG; COG0827; Bacteria.
DR   eggNOG; COG4646; Bacteria.
DR   HOGENOM; CLU_000181_2_0_9; -.
DR   Proteomes; UP000007059; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01624; MutS_I; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Methyltransferase {ECO:0000313|EMBL:CBL02126.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Transferase {ECO:0000313|EMBL:CBL02126.1}.
FT   DOMAIN          1266..1515
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
SQ   SEQUENCE   1551 AA;  175242 MW;  B525A221A862F6C0 CRC64;
     MGGKQRIMAL YQTQPDRKLR AKALAKEYGI GGHSHDFLDG SRGFVNHNWK GLEFDHYPDH
     QKITLKWAQV EKYIDLMIQS DRYLTDKEKE HYTSPAPVNA KPDGAIDHAK NLIREFCQEE
     YDSEPDFSDL SKIGIAYTNA TDEEIPIQVN VDLVGYRVER YLGEVLINER QYESLEELTE
     TELEALDFSE LVSVTDEELE HYHNKADERP ALLPLDAATE YNALKEQHPD ALVGFEQNGQ
     FEFYGEDARK VCELLGGKFL EKETALGTVP VISFPRNQWA YRAKQLWQRG ENVYLAGLNE
     DGTHHQTKYL RREDYLPLGA TVHMEGRAFR VDTVNFDKGS VTLQDVALAE MRMPIFREEP
     LALVRELYEQ EQEVMEHTLP AYKVGDNVIV DLPSRTIEGK IGYVGETDVR IDTSAQGQSW
     DNEVINKQQF EDGLRQVEPE LSDEELDALP ISTVMDGKVQ TFPDAAALDE ALNTEPAPEP
     AGNFRITDDH LGEGGAKQKY ARNIEAIRTL FKLEEEHRGA TAEEQQVLSQ YVGWGGLADA
     FDPNKENWSA EYTQLKELLS EDEYAAARAS TLNAHYTGPT VIRGIYDAVE RMGFQSGNIL
     EPSMGVGNFF GMLPTSMADS RLYGVELDSI TGRIAKKLYP QADITVAGFE TTDRRDFYDL
     AVGNVPFGQY KVNDKAYNKL GFSIHNYFFA KAIDQIRPGG VIAFVTSRYT MDSKDSTARK
     HMAERADLLG AIRLPNNAFR ANAGTDVVSD IIFLQKRDRP ADIEPAWVQL GKTEDGFAIN
     QYFADRPEMV LGVLSTESTQ YGREELTVAP IEGANLANQL AEAVQHIEGQ YTAAEVDAPD
     IAEEETTRRT LPADPEVKNF SYTVVDGEVF YRENSVMTQV ELSDTAKGRV TGMVELRQIV
     NDLIEQQLND YPDEDIKATQ ERLNAVYDAF TAKYGLLNDR KNGRLFEQDS SYYLLCSLEN
     LDEQGQLKSK AAMFTKRTIR PERTVTSVDT PSEALAVSIG EHGKVDLPYM AELLGTPGDY
     GRITAELSGV IFKDPAADPT DPEAGWQMAD EYLSGDVRAK LRMAQFAAET NPEFSVNVEA
     LTKAQPRELE ASEIDVRLGA TWLDPSIIQK FMTETFQIPY YLRHAVKVRY SQYTAEWRVE
     GKTATGRSDI ISSETYGTSR ANAYKILEET LNLKDVRIYD TIEDAEGKPK RVLNKRETML
     AQQKQQVIKD AFANWVWQDP QRRIALVRQY NELFNSTRPR EYDGSHIHFV GMNPEISLRE
     HQRNAIAHVL YGGNTLLAHE VGAGKTFEMA ASAMEAKRLG LCQKSLFVVP NHLTEQWASE
     FLHLYPNAKL LVARRKDFET ANRKKFCARI ATGDYDAVII GHSQFERIPL SFERQERIIQ
     DQIVETLLAI NELKANAGEN FTIKQMERTR KTLEAKLDKL RADSRKDDVI TFEQLGVDRL
     FVDESHSFKN LFLTTKMRNV AGLSTSEAQK SSDMFGKCRY LDEITGGRGV VFATGTPISN
     SMTELYTVMR YLQYSTLQQK KLTHFDCWAS TFGETTTAIE LAPEGYTLIG R
//