ID D4L1D2_9FIRM Unreviewed; 502 AA.
AC D4L1D2;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Arginine/lysine/ornithine decarboxylases {ECO:0000313|EMBL:CBL13422.1};
DE EC=4.1.1.18 {ECO:0000313|EMBL:CBL13422.1};
GN ORFNames=RO1_30780 {ECO:0000313|EMBL:CBL13422.1};
OS Roseburia intestinalis XB6B4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=718255 {ECO:0000313|EMBL:CBL13422.1, ECO:0000313|Proteomes:UP000008953};
RN [1] {ECO:0000313|EMBL:CBL13422.1, ECO:0000313|Proteomes:UP000008953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XB6B4 {ECO:0000313|EMBL:CBL13422.1,
RC ECO:0000313|Proteomes:UP000008953};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Bernalier A.;
RT "The genome sequence of Roseburia intestinalis XB6B4.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL13422.1, ECO:0000313|Proteomes:UP000008953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XB6B4 {ECO:0000313|EMBL:CBL13422.1,
RC ECO:0000313|Proteomes:UP000008953};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
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DR EMBL; FP929050; CBL13422.1; -; Genomic_DNA.
DR AlphaFoldDB; D4L1D2; -.
DR KEGG; rix:RO1_30780; -.
DR PATRIC; fig|718255.3.peg.405; -.
DR HOGENOM; CLU_025925_1_1_9; -.
DR Proteomes; UP000008953; Chromosome.
DR GO; GO:0008923; F:lysine decarboxylase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CBL13422.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 6..289
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 403..471
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
SQ SEQUENCE 502 AA; 56338 MW; EB7BC5C675669EF0 CRC64;
MRYLDQALEA YGKSDVYPFH MPGHKRNPLP FPEVYGIDIT EIDGFDNLHH AEGILKEAQQ
RAADLYGSAH CYYLVNGSTC GILASICAAV KKRGRILVAR NSHKAVYHAL FLSELTAEYL
YPAVTECGIQ GQITPRQVED ALKKDPETSA VVITSPTYEG VISDIEGIAK VAHVHGIPLI
VDSAHGAHLG FGGEFPQNAV RLGADAVIES LHKTLPSFTQ TALLHLNSDL ISKSRIEKYL
GIYETSSPSY ILMAGMEVCI RTVKEHGAEL FDNYRHELNK FYKNCEDLKR LHVMTGKDLS
KEEAFAWDDS KIVIFVRDSS KSGEWLYQEL LLKYHLQLEM ASGDYALAMT SIMDQEEGYQ
RLSAALHEID RELCGADTAK KQQVMNEKKV RYGNETDGSM ENMYEQQVHR GSFIKEVYRP
NPAQMQIYEA EEKETAEVSF DEAAGRVSAD FIFLYPPGIP LIVPGESITA EFIERLRTCI
SLKLNLQGST DLFAERIKIV YF
//
