ID D4LAX6_RUMC1 Unreviewed; 568 AA.
AC D4LAX6;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain {ECO:0000313|EMBL:CBL16771.1};
GN OrderedLocusNames=RUM_05510 {ECO:0000313|EMBL:CBL16771.1};
OS Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / KCTC 15320 /
OS 18P13).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=213810 {ECO:0000313|EMBL:CBL16771.1, ECO:0000313|Proteomes:UP000007054};
RN [1] {ECO:0000313|Proteomes:UP000007054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18848 / JCM 17042 / 18P13
RC {ECO:0000313|Proteomes:UP000007054};
RA Pajon A., Turner K., Parkhill J., Bernalier A.;
RT "The genome sequence of Ruminococcus sp. 18P13.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FP929052; CBL16771.1; -; Genomic_DNA.
DR RefSeq; WP_015557678.1; NC_021039.1.
DR AlphaFoldDB; D4LAX6; -.
DR STRING; 213810.RUM_05510; -.
DR GeneID; 83155367; -.
DR KEGG; rch:RUM_05510; -.
DR PATRIC; fig|213810.4.peg.457; -.
DR HOGENOM; CLU_000445_70_50_9; -.
DR BioCyc; RCHA213810:RUM_RS02660-MONOMER; -.
DR Proteomes; UP000007054; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007054};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 165..303
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 312..565
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 568 AA; 64043 MW; A806B9AE44254E06 CRC64;
MAKSRMEFTK NQTEWIVLTL LALLLLLFQL ITSRLTRYGG TFAIGETELE YGRLCSIFNV
LQIFTGMLMV INTKRKGWIC MSILSILNLI MVISTVFVQQ QVNNLPGVAM QALNLIICST
IYFYVRKCDI NAARLDEVAN TDELTGLPNR RSLLRHVNRR ISKGTPFAFV LLDLDNFKSI
NDTAGHEYGD EILQQIAQRW KEQVQNKNAF FARLGGDEFV LITDYNGDLG KLEQMLHEAI
NRAPSDKRTR FSVRDSSFFI TASMGISLFP EHADNVSTLM SYADIAMYQA KARGRQGLCM
FRQEMDSALT DNLQIEQMLR DALQENRFFL AFQPQYHISD HSLRGFETLV RMRDAKGNQV
SPGRFIPVAE ASALMIQLDQ WIMGNALTCM QPVVAQHPDI ILSVNVSARN LLHGDFSTYV
QNLLRSTGFP ARNLELEVTE SLFISSLEHA SKILNRLRDI GIRIALDDFG TGYASLSYLN
RLPIDLLKID KSFIDQINSD TNGNAFVKAI ITMGHVLGCE VISEGVESDS QLDVLKGYAC
DLLQGFLWGK PLSFEEAKQL AQKEPIPS
//
