ID   D4LUP9_9FIRM            Unreviewed;       499 AA.
AC   D4LUP9;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   03-APR-2013, entry version 14.
DE   RecName: Full=L-arabinose isomerase;
DE            EC=5.3.1.4;
GN   Name=araA; ORFNames=CK5_33060;
OS   Ruminococcus obeum A2-162.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae;
OC   Blautia.
OX   NCBI_TaxID=657314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A2-162;
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Ruminococcus obeum A2-162.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the conversion of L-arabinose to L-ribulose
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: L-arabinose = L-ribulose.
CC   -!- COFACTOR: Binds 1 manganese ion per subunit (By similarity).
CC   -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC       ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial
CC       route): step 1/3.
CC   -!- SIMILARITY: Belongs to the arabinose isomerase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; FP929054; CBL24507.1; -; Genomic_DNA.
DR   ProteinModelPortal; D4LUP9; -.
DR   EnsemblBacteria; CBL24507; CBL24507; CK5_33060.
DR   PATRIC; 43165630; VBIRumObe156199_3199.
DR   UniPathway; UPA00145; UER00565.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008733; F:L-arabinose isomerase activity; IEA:HAMAP.
DR   GO; GO:0008736; F:L-fucose isomerase activity; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00519; Arabinose_Isome; 1; -.
DR   InterPro; IPR024664; Ara_Isoase_C.
DR   InterPro; IPR004216; Fuc/Ara_isomerase_C.
DR   InterPro; IPR009015; Fucose_isomerase_N/cen.
DR   InterPro; IPR003762; Lara_isomerase.
DR   Pfam; PF11762; Arabinose_Iso_C; 1.
DR   Pfam; PF02610; Arabinose_Isome; 1.
DR   PIRSF; PIRSF001478; L-ara_isomerase; 1.
DR   SUPFAM; SSF50443; Fuc_isomerase_C; 1.
DR   SUPFAM; SSF53743; Fuc_isomerase_N; 1.
PE   3: Inferred from homology;
KW   Arabinose catabolism; Carbohydrate metabolism; Isomerase; Manganese;
KW   Metal-binding.
FT   METAL       306    306       Manganese (By similarity).
FT   METAL       335    335       Manganese (By similarity).
FT   METAL       352    352       Manganese (By similarity).
FT   METAL       451    451       Manganese (By similarity).
SQ   SEQUENCE   499 AA;  56408 MW;  E4E1E31F26B88FE2 CRC64;
     MVTGKNYKFW FCTGSQDLYG DECLRKVAEH SKIIVEELNK SGALPFELVW KPTLITNELI
     RKTFNEANDD EECAGVITWM HTFSPAKSWI LGLKEYRKPL CHLHTQFNQE IPYDTIDMDF
     MNENQSAHGG REYGHIVTRM GIERKVIVGH WADKKVQERL ASWMRTAVGI MESSHIRVCR
     VADNMRNVAV TEGDKVEAQI KFGWEVDAYP VNEVCDYVKD VSKGDIDVLV EEYYNKYDIL
     LEGRNPEEFK RHVAVQAAIE IGFERFLEEK NYQAVVTHFG DLGGLQQLPG LAMQRLMEKG
     YGFGAEGDWK TAAMVRLMKI MTAGVKDAKG TSFMEDYTYN LVSGKEGILQ SHMLEVCPTI
     ADGKIGIKVC PLSMGEREDP ARLVFTSKTG PAIATSLIDL GDRFRLIIND VECKKVEKPM
     PKLPVGSAFW TPQPDLATGA EAWILAGGAH HTAFSYDLTA EQMGDWAAAM GIEAVYIDKD
     TTIRNFKNEL RWNELAFRK
//