ID D4LXQ0_9FIRM Unreviewed; 598 AA.
AC D4LXQ0;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=Beta-lactamase class D {ECO:0000313|EMBL:CBL22403.1};
GN ORFNames=CK5_08890 {ECO:0000313|EMBL:CBL22403.1};
OS Blautia obeum A2-162.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=657314 {ECO:0000313|EMBL:CBL22403.1, ECO:0000313|Proteomes:UP000008955};
RN [1] {ECO:0000313|EMBL:CBL22403.1, ECO:0000313|Proteomes:UP000008955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2-162 {ECO:0000313|EMBL:CBL22403.1,
RC ECO:0000313|Proteomes:UP000008955};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Ruminococcus obeum A2-162.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL22403.1, ECO:0000313|Proteomes:UP000008955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2-162 {ECO:0000313|EMBL:CBL22403.1,
RC ECO:0000313|Proteomes:UP000008955};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M56 family.
CC {ECO:0000256|ARBA:ARBA00011075}.
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DR EMBL; FP929054; CBL22403.1; -; Genomic_DNA.
DR RefSeq; WP_015541271.1; NC_021022.1.
DR AlphaFoldDB; D4LXQ0; -.
DR KEGG; rob:CK5_08890; -.
DR PATRIC; fig|657314.3.peg.654; -.
DR HOGENOM; CLU_035412_0_2_9; -.
DR Proteomes; UP000008955; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd07341; M56_BlaR1_MecR1_like; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR008756; Peptidase_M56.
DR PANTHER; PTHR34978; POSSIBLE SENSOR-TRANSDUCER PROTEIN BLAR; 1.
DR PANTHER; PTHR34978:SF3; SLR0241 PROTEIN; 1.
DR Pfam; PF05569; Peptidase_M56; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..309
FT /note="Peptidase M56"
FT /evidence="ECO:0000259|Pfam:PF05569"
FT DOMAIN 391..592
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 598 AA; 68364 MW; 77F75BE3C1B6BA4E CRC64;
MSNWIIHFLI SNIFICIFTL VIIGTKKLLK KYLSATTQYH LCFLLFLLLA VPFFPVQIHG
SQLFSWLHFF QTDSGLNSGT DTLSELTSNT QNILLNQVND FSVSISSQFS GGLNTILFLI
WITGVMIMSV LTLHSLNYVR SIKRSALPLQ NQQVKTIYYN CLKELKISHP VSVYSTAFLK
SPVLIGIIHP RIYIPIHLIS ELNPDDMRFM LLHELQHYRH KDTFIGFLMV ISNILYWFNP
FVWYTLKEIL CDREIACDSA VLQMISADEY QAYGTTLINF AEKISSFSSP LAVGMSGNFR
QMKRRILNIA VFRKETLYQK MRALIIYLVI SAVFIGCTPI LSIDASTQNV YHFSDTDKNI
SLLDISETFG TYDGSFVLYD NNLDSWKIYD LEEATKRIPP ESTYKIYDAL LGLESGIITP
EHSSMTWNGD AFPFPSWEAD QDLNSAMQNS VNWYFQAIDS QLGINRVQEF LNKIEYGNQT
TSSNLDLYWS DFSLKISPLE QVTLLKKFNT NEFHLNFQNV FSVKNAIKIA STPNGNFYGK
TGTGRVNGQD INGWFIGYVE TSDNSYYFAT NIQSDSNATG KKAFEITSDI LKKLHIWN
//
