ID D4M000_9FIRM Unreviewed; 383 AA.
AC D4M000;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative GTPases (G3E family) {ECO:0000313|EMBL:CBL27360.1};
GN ORFNames=RTO_29440 {ECO:0000313|EMBL:CBL27360.1};
OS [Ruminococcus] torques L2-14.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Mediterraneibacter.
OX NCBI_TaxID=657313 {ECO:0000313|EMBL:CBL27360.1, ECO:0000313|Proteomes:UP000008956};
RN [1] {ECO:0000313|EMBL:CBL27360.1, ECO:0000313|Proteomes:UP000008956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-14 {ECO:0000313|EMBL:CBL27360.1,
RC ECO:0000313|Proteomes:UP000008956};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Ruminococcus torques L2-14.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL27360.1, ECO:0000313|Proteomes:UP000008956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-14 {ECO:0000313|EMBL:CBL27360.1,
RC ECO:0000313|Proteomes:UP000008956};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; FP929055; CBL27360.1; -; Genomic_DNA.
DR AlphaFoldDB; D4M000; -.
DR STRING; 33039.ERS852502_02432; -.
DR KEGG; rto:RTO_29440; -.
DR PATRIC; fig|657313.3.peg.2831; -.
DR HOGENOM; CLU_017452_1_3_9; -.
DR Proteomes; UP000008956; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 6..179
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT DOMAIN 316..381
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07683"
FT REGION 211..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 43325 MW; 9521390944A6F9BB CRC64;
MTKIDIISGF LGAGKTTLIK KLLSDAYKGE QVVLIENEFG EIGIDGGFLK EAGIEIREMN
SGCICCSLVG DFGKSLHEVV DTYHPDRILI EPSGVGKLSD VIKAVQDVQG EIDAELNSFT
TVVDVTKCKI YRKNFGEFFS NQIEYAGAVI LSRTDKAKPE KIQESVALLR ELNEKAPIIT
TPIEQLPGEK ILETMESSKS LEDELLAEVS KEAHDHEHHH HHDHEECDHE HHHHHDHEEC
DHEHHHHHDH EECDHEHHHH DHEEHEHHHH DGECSCGCGH HHHDHEGHHH ADEVFTSWGK
ETIHTYTKDE VSAILKTLEE DGSYGNVLRA KGMVAGADGE WIYFDMVPEE HEVRTGAPEY
TGRICVIGAE LNEDKLAELF KVK
//
