ID D4MLK5_9FIRM Unreviewed; 311 AA.
AC D4MLK5;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Mg2+ and Co2+ transporters {ECO:0000313|EMBL:CBL34638.1};
GN ORFNames=ES1_17070 {ECO:0000313|EMBL:CBL34638.1};
OS [Eubacterium] siraeum V10Sc8a.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=717961 {ECO:0000313|EMBL:CBL34638.1, ECO:0000313|Proteomes:UP000007050};
RN [1] {ECO:0000313|EMBL:CBL34638.1, ECO:0000313|Proteomes:UP000007050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V10Sc8a {ECO:0000313|EMBL:CBL34638.1,
RC ECO:0000313|Proteomes:UP000007050};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Eubacterium siraeum V10Sc8a.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL34638.1, ECO:0000313|Proteomes:UP000007050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V10Sc8a {ECO:0000313|EMBL:CBL34638.1,
RC ECO:0000313|Proteomes:UP000007050};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; FP929059; CBL34638.1; -; Genomic_DNA.
DR AlphaFoldDB; D4MLK5; -.
DR KEGG; esr:ES1_17070; -.
DR PATRIC; fig|717961.3.peg.1800; -.
DR HOGENOM; CLU_007127_8_1_9; -.
DR BioCyc; ESIR717961:G136L-1415-MONOMER; -.
DR Proteomes; UP000007050; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12827; EcCorA_ZntB-like_u2; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR047199; CorA-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR47891:SF2; MAGNESIUM AND COBALT TRANSPORTER; 1.
DR PANTHER; PTHR47891; TRANSPORTER-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 311 AA; 35586 MW; 8E38F82F67D54F29 CRC64;
MLKYYKTVEN TIVELDTMEP GCWVSAVAPT ETEISSLQEE LNIDRDFIRS ALDEEETSRI
ESDDGQTLIV LDYPVAEKIQ DKDDTISYYT MPMGIIITDS HVVTVCLKEN IIIDEFTKGI
VKGIQTQFKT RFVFHMLLRI AGKYLLYLKQ IDKLSNYVEQ QLHKSMKNKE LIQLLGLEKS
LVYFSTSLKS TETVLEKILR GRVIKLYEED QELLEDVLIE VKQAIEMSNI YSNILSGTMD
AFASVISNNL NIVMKVLTVI TIVMSVPTMV FSFYGMNVLD LPLPYTWFPV LISVILAVIV
AILITKNKFY K
//
