ID   D4MNB3_9FIRM            Unreviewed;       416 AA.
AC   D4MNB3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   SubName: Full=Endoglucanase {ECO:0000313|EMBL:CBL35246.1};
GN   ORFNames=ES1_24330 {ECO:0000313|EMBL:CBL35246.1};
OS   [Eubacterium] siraeum V10Sc8a.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=717961 {ECO:0000313|EMBL:CBL35246.1, ECO:0000313|Proteomes:UP000007050};
RN   [1] {ECO:0000313|EMBL:CBL35246.1, ECO:0000313|Proteomes:UP000007050}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V10Sc8a {ECO:0000313|EMBL:CBL35246.1,
RC   ECO:0000313|Proteomes:UP000007050};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Eubacterium siraeum V10Sc8a.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBL35246.1, ECO:0000313|Proteomes:UP000007050}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V10Sc8a {ECO:0000313|EMBL:CBL35246.1,
RC   ECO:0000313|Proteomes:UP000007050};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|RuleBase:RU361153}.
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DR   EMBL; FP929059; CBL35246.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4MNB3; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   KEGG; esr:ES1_24330; -.
DR   PATRIC; fig|717961.3.peg.38; -.
DR   HOGENOM; CLU_018668_2_1_9; -.
DR   BioCyc; ESIR717961:G136L-2043-MONOMER; -.
DR   Proteomes; UP000007050; Chromosome.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31297:SF41; ENDOGLUCANASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01830)-RELATED; 1.
DR   PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW   Hydrolase {ECO:0000256|RuleBase:RU361153};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..416
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038616796"
FT   DOMAIN          98..382
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   REGION          25..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  47082 MW;  E4623BC070094572 CRC64;
     MKKRLTAILT VTALLLTGCA GNVTSGTESQ PVSDAQSGIS DNESSDTSSR YEIITATEMA
     EKMGLGISLG NTMEAYEATD CEKITYEWIP VVGGNEPQDY ETCWGADVTT QEIIDGMKAE
     GFNTVRIPVF WGNMMENDNT YTINKEYLKR VKEIVDYCEK AGVYSVINIH HFDEFIIRRN
     DLDKCKEIFT HLWTQIAEYF ADYPYTLVFE GYNEYLGGNQ FDSNGNLKEQ SETNAYKMTN
     TLNQAFVDAV RGTGGYNAQR VLIVSGYWTN IDKTTSSRFQ MPEDMVNDRL MVSVHYVDNS
     MYWSNKIGGE EWLKYIDSQC AELKKAFLDN DIPVFMGETT STYPASNMAK DATHTDSSEC
     LSIVLGKLTE LGIVPVIWDT DSHFYSRTTY KIVNESDRKV IREYSDKLKA NLEAQQ
//