ID D4MUW7_ANAHA Unreviewed; 684 AA.
AC D4MUW7;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Probable licABCH operon regulator {ECO:0000313|EMBL:CUM75765.1};
DE SubName: Full=Transcriptional antiterminator {ECO:0000313|EMBL:CBL39183.1};
GN Name=licR_4 {ECO:0000313|EMBL:CUN77193.1};
GN Synonyms=licR_1 {ECO:0000313|EMBL:CUM75765.1};
GN ORFNames=CL2_23240 {ECO:0000313|EMBL:CBL39183.1}, DO83_04540
GN {ECO:0000313|EMBL:AQP38934.1}, ERS852475_00767
GN {ECO:0000313|EMBL:CUN77193.1}, ERS852520_00582
GN {ECO:0000313|EMBL:CUP08870.1}, ERS852571_00425
GN {ECO:0000313|EMBL:CUM75765.1};
OS Anaerostipes hadrus.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerostipes.
OX NCBI_TaxID=649756 {ECO:0000313|EMBL:CBL39183.1, ECO:0000313|Proteomes:UP000008960};
RN [1] {ECO:0000313|EMBL:CBL39183.1, ECO:0000313|Proteomes:UP000008960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSC/2 {ECO:0000313|EMBL:CBL39183.1,
RC ECO:0000313|Proteomes:UP000008960};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Clostridiales sp. SSC/2.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL39183.1, ECO:0000313|Proteomes:UP000008960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSC/2 {ECO:0000313|EMBL:CBL39183.1,
RC ECO:0000313|Proteomes:UP000008960};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000095553, ECO:0000313|Proteomes:UP000095564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5834860 {ECO:0000313|EMBL:CUN77193.1,
RC ECO:0000313|Proteomes:UP000095611}, 2789STDY5834908
RC {ECO:0000313|EMBL:CUP08870.1, ECO:0000313|Proteomes:UP000095564}, and
RC 2789STDY5834959 {ECO:0000313|EMBL:CUM75765.1,
RC ECO:0000313|Proteomes:UP000095553};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AQP38934.1, ECO:0000313|Proteomes:UP000188159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BPB5 {ECO:0000313|EMBL:AQP38934.1,
RC ECO:0000313|Proteomes:UP000188159};
RX PubMed=27264309; DOI=10.1038/srep27572;
RA Zhang Q., Wu Y., Wang J., Wu G., Long W., Xue Z., Wang L., Zhang X.,
RA Pang X., Zhao Y., Zhao L., Zhang C.;
RT "Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced
RT colitis by a butyrate-producing bacterium.";
RL Sci. Rep. 6:27572-27572(2016).
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DR EMBL; CP012098; AQP38934.1; -; Genomic_DNA.
DR EMBL; FP929061; CBL39183.1; -; Genomic_DNA.
DR EMBL; CYXY01000002; CUM75765.1; -; Genomic_DNA.
DR EMBL; CYZM01000002; CUN77193.1; -; Genomic_DNA.
DR EMBL; CZAU01000003; CUP08870.1; -; Genomic_DNA.
DR RefSeq; WP_015530698.1; NZ_WQRB01000005.1.
DR AlphaFoldDB; D4MUW7; -.
DR GeneID; 15233035; -.
DR KEGG; bprl:CL2_23240; -.
DR PATRIC; fig|245018.3.peg.2611; -.
DR Proteomes; UP000008960; Chromosome.
DR Proteomes; UP000095553; Unassembled WGS sequence.
DR Proteomes; UP000095564; Unassembled WGS sequence.
DR Proteomes; UP000095611; Unassembled WGS sequence.
DR Proteomes; UP000188159; Chromosome.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd05568; PTS_IIB_bgl_like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 286..393
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 397..483
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 534..683
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 684 AA; 79938 MW; EA3716A77EE71707 CRC64;
MSIVYNLDVR CHEMLKYLLY QDGYTSITQL AEEMNISKRS VYYDIRKINE WMEAQHLSEL
VVERKKGIRI DDEQKAMIRA GLKMIPSELA YVFTPTERVK IIICSILQRN RNLFLDDFMD
FCQVSRNTTI SDVKEAGRII SEYQLQLIYE NGKGYHIKGD LVRKRSIYFS YFSSIADFYK
KGILPLDAPE KVQEFLDRLK DIENALDVQY VQGTLYTIAV FFSTIDNRTD VVEFSKKEKM
EIMDTKEYEM VSRRFSDLKE SEQLYLTLHL LGSRMQSIPV DFMEEESGQE SQWLSRILVK
AFSRIAGVGF SKERELTEAL AAHLKTSMYR YRYGVQLANP MLDNIKNEYG DLFELTARTC
KYLEKEIGFP IPEGEIAYIT LHFGAFISAG QEKENRLRIL IVCPNGVSTA NMIWGEIQTL
VPDADVVDVC SLREYERAHD YNVVISTVVI ENEKDLILVH PILTDNDRMK VLQRCMKYKH
ENNVSISNIT EIASKYMTND NLQKFKEELI ELFSKNSLKQ YVEHKKKPQK GLYEILEDPY
IRIIKDKFKW QDAIKVSGEV LLENKLIRQS YIDSIIYKTD QYGPYMFITK QVFLAHSEIE
DGAQSMGLSM TIFKKPVEFI TLDGKQRFAK IILMLSAQDQ KSHIRLLNDI MTIFSEQKNE
EKLWGQKEIL DVKNVLYELL QEEK
//
