ID D4MX17_ANAHA Unreviewed; 495 AA.
AC D4MX17;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Iron only hydrogenase large subunit, C-terminal domain {ECO:0000313|EMBL:CBL37162.1};
DE EC=1.12.7.2 {ECO:0000313|EMBL:CBL37162.1};
GN ORFNames=CL2_00380 {ECO:0000313|EMBL:CBL37162.1};
OS Anaerostipes hadrus.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerostipes.
OX NCBI_TaxID=649756 {ECO:0000313|EMBL:CBL37162.1, ECO:0000313|Proteomes:UP000008960};
RN [1] {ECO:0000313|EMBL:CBL37162.1, ECO:0000313|Proteomes:UP000008960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSC/2 {ECO:0000313|EMBL:CBL37162.1,
RC ECO:0000313|Proteomes:UP000008960};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Clostridiales sp. SSC/2.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL37162.1, ECO:0000313|Proteomes:UP000008960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSC/2 {ECO:0000313|EMBL:CBL37162.1,
RC ECO:0000313|Proteomes:UP000008960};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FP929061; CBL37162.1; -; Genomic_DNA.
DR RefSeq; WP_008392956.1; NC_021016.1.
DR AlphaFoldDB; D4MX17; -.
DR STRING; 649756.ERS852387_01540; -.
DR GeneID; 15230253; -.
DR KEGG; bprl:CL2_00380; -.
DR PATRIC; fig|245018.3.peg.29; -.
DR Proteomes; UP000008960; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd10549; MtMvhB_like; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR000813; 7Fe_ferredoxin.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR027631; Mono_FeFe_hydrog.
DR NCBIfam; TIGR04105; FeFe_hydrog_B1; 1.
DR PANTHER; PTHR11615:SF368; HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF00037; Fer4; 2.
DR PRINTS; PR00354; 7FE8SFRDOXIN.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 3.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:CBL37162.1}.
FT DOMAIN 110..140
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 141..170
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 187..216
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 495 AA; 54110 MW; 3B79B6564AEA9D2E CRC64;
MRGIQTPVRN VRRRIFKEIA KFGYEQRNLQ DLEDLPYEIV PGEVAKYRDS IYRERAIVGE
RLRLAMGMSL NPADKPTRIT KEIDESNISE KYYEPPLLQV IPSACNECKE KAFIVGEQCQ
GCMAHPCMEV CPKKAISFKD GYSYIDQEKC IKCGQCKKVC PYGAIYERKR PCANACGVGA
IETDYAGRAK INPDKCVSCG MCMVNCPFGA IADKSQIYQL IKAMNEGAEV IAILAPAFVG
QFGPKATPNK IKAALLDIGF ADVWEVAVGA DAGALEEAKH YVQSVATGKL PFLLTSCCPS
WSMLGKKYFP EVIDEISNAL TPMVATARAA RIASPNAKIV FVGPCVAKKL EASRRTVRSE
VDFVITFEEL AGMFDAKEID FNTYEKEEEL NDAFGAGRGY AVASGVAGAI KACIDEYYPG
TEVKIDHVEG LADCKKMLLQ AKAGKKKGYL IEGMGCPGGC VAGAGTNIPV MKAQIQVKKF
VKEAEDFVPP ETAQY
//
