ID D4S6M0_9FIRM Unreviewed; 162 AA.
AC D4S6M0;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=siroheme decarboxylase {ECO:0000256|ARBA:ARBA00023471};
DE EC=4.1.1.111 {ECO:0000256|ARBA:ARBA00023471};
GN ORFNames=HMPREF7545_1185 {ECO:0000313|EMBL:EFF66145.1};
OS Selenomonas noxia ATCC 43541.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Selenomonas.
OX NCBI_TaxID=585503 {ECO:0000313|EMBL:EFF66145.1, ECO:0000313|Proteomes:UP000003701};
RN [1] {ECO:0000313|EMBL:EFF66145.1, ECO:0000313|Proteomes:UP000003701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43541 {ECO:0000313|EMBL:EFF66145.1,
RC ECO:0000313|Proteomes:UP000003701};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + siroheme = 12,18-didecarboxysiroheme + 2 CO2;
CC Xref=Rhea:RHEA:19093, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:60052, ChEBI:CHEBI:140497; EC=4.1.1.111;
CC Evidence={ECO:0000256|ARBA:ARBA00023409};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the Ahb/Nir family.
CC {ECO:0000256|ARBA:ARBA00023457}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFF66145.1}.
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DR EMBL; ACKT01000023; EFF66145.1; -; Genomic_DNA.
DR RefSeq; WP_006695554.1; NZ_GG749283.1.
DR AlphaFoldDB; D4S6M0; -.
DR eggNOG; COG1522; Bacteria.
DR HOGENOM; CLU_112007_0_1_9; -.
DR InParanoid; D4S6M0; -.
DR OrthoDB; 9806536at2; -.
DR Proteomes; UP000003701; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 3.30.70.3460; -; 1.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR040523; AsnC_trans_reg2.
DR PANTHER; PTHR43413:SF1; SIROHEME DECARBOXYLASE NIRL SUBUNIT; 1.
DR PANTHER; PTHR43413; TRANSCRIPTIONAL REGULATOR, ASNC FAMILY; 1.
DR Pfam; PF17805; AsnC_trans_reg2; 1.
DR Pfam; PF13404; HTH_AsnC-type; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 9..51
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|Pfam:PF13404"
FT DOMAIN 68..152
FT /note="Siroheme decarboxylase AsnC-like ligand binding"
FT /evidence="ECO:0000259|Pfam:PF17805"
SQ SEQUENCE 162 AA; 18646 MW; 2F18FE839EC2662E CRC64;
MTEGTGISEL DKKIVRLLQG EFPLVSEPYK VLAAEIGISE EELLARVAAL REEKKIRKIG
AVLRHREVGF TSNCLCVWDV PDECMDETAA RMAEHPRVSH CYERNRATGW HYNLYTMIHG
YSREECEAIA AELSTATGIA DRRMLYTKKE WKKTAMRYFT EE
//
