ID D4YNG1_9MICO Unreviewed; 440 AA.
AC D4YNG1;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=PhoH family protein {ECO:0000313|EMBL:EFG47207.1};
GN ORFNames=HMPREF0183_1471 {ECO:0000313|EMBL:EFG47207.1};
OS Brevibacterium mcbrellneri ATCC 49030.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=585530 {ECO:0000313|EMBL:EFG47207.1, ECO:0000313|Proteomes:UP000005714};
RN [1] {ECO:0000313|EMBL:EFG47207.1, ECO:0000313|Proteomes:UP000005714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49030 {ECO:0000313|EMBL:EFG47207.1,
RC ECO:0000313|Proteomes:UP000005714};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG47207.1}.
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DR EMBL; ADNU01000043; EFG47207.1; -; Genomic_DNA.
DR RefSeq; WP_005884463.1; NZ_ADNU01000043.1.
DR AlphaFoldDB; D4YNG1; -.
DR STRING; 585530.HMPREF0183_1471; -.
DR eggNOG; COG1875; Bacteria.
DR OrthoDB; 9766527at2; -.
DR Proteomes; UP000005714; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000005714};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 6..133
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
SQ SEQUENCE 440 AA; 47672 MW; C3B299B3B99A41E0 CRC64;
MTTTVHTYVL DTSVLLSDPR AIYRFDEHDV VIPLIVVSEL EAKRHHPELG FTARRALGIL
DDLREEFGRL DAPIPIGSEG GTLRVELNHV DASGLPVAFD RGENDTRILA VARNLQAEGH
SVVVVTKDVP MRVKASALGL AAEAYLAEQA VDSGYTGLSE LMLDEAEMAQ LFDSGFVETK
AAGAEVLNTG LVLSSSRGSG LGRVVALNEQ AGTGTIKLVR GDRDVFGIHG RSAEQRIALD
MLTDEEVGIV SLGGRAGTGK SAMALMAGLQ AVLEDRTHEK IMVFRPLYAV GGQNLGYLPG
DESDKMNPWA EAVFDTLGAL VSRNVIDEVI HRGMLEVLPL THIRGRSLHD AFVIVDEAQS
LERTVLLTVL SRLGQNSRVV LTHDVAQRDN LRVGRHDGIS AVIEKLKGYK LFAHITLTRS
ERSAIAALVT QVLEEFDMHT
//
