ID   D4YU66_9LACO            Unreviewed;       334 AA.
AC   D4YU66;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=Bacterial type II secretion system domain protein F {ECO:0000313|EMBL:EFG55277.1};
GN   Name=comGB {ECO:0000313|EMBL:EFG55277.1};
GN   ORFNames=HMPREF0493_1077 {ECO:0000313|EMBL:EFG55277.1};
OS   Lactobacillus amylolyticus DSM 11664.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=585524 {ECO:0000313|EMBL:EFG55277.1, ECO:0000313|Proteomes:UP000004069};
RN   [1] {ECO:0000313|EMBL:EFG55277.1, ECO:0000313|Proteomes:UP000004069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11664 {ECO:0000313|EMBL:EFG55277.1,
RC   ECO:0000313|Proteomes:UP000004069};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the GSP F family.
CC       {ECO:0000256|ARBA:ARBA00005745}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFG55277.1}.
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DR   EMBL; ADNY01000041; EFG55277.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4YU66; -.
DR   STRING; 83683.B1745_04450; -.
DR   eggNOG; COG1459; Bacteria.
DR   Proteomes; UP000004069; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR   InterPro; IPR003004; GspF/PilC.
DR   InterPro; IPR018076; T2SS_GspF_dom.
DR   InterPro; IPR042094; T2SS_GspF_sf.
DR   PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR   PANTHER; PTHR30012:SF0; TYPE II SECRETION SYSTEM PROTEIN F-RELATED; 1.
DR   Pfam; PF00482; T2SSF; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004069};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..138
FT                   /note="Type II secretion system protein GspF"
FT                   /evidence="ECO:0000259|Pfam:PF00482"
FT   DOMAIN          208..326
FT                   /note="Type II secretion system protein GspF"
FT                   /evidence="ECO:0000259|Pfam:PF00482"
SQ   SEQUENCE   334 AA;  37669 MW;  DCE43AD6608639D7 CRC64;
     MNMLTVSSKK DKLNGEEQLE FLDYLKSSLK NGFSLNSSLE LMAVMWPKKR QLLIALNQRM
     QNGGSLTTEL LRLGFSKTTV TQINLALSQG NLVECLSQLT IINRLKNQQI KKLWVELSYP
     FVLAGMMIVL LLFMQTFVST QFQESSNYTG DIILLSLVVI IGGGVFYFAK MLTLLAKQDY
     ASLKKLSKYA FIGKTIRTYV NYLVVYDIGM LLASGFSLQK MCEYAAKQYA GSLQQYLGEK
     IGERLNQGIS LEKIIKEEDF LPDNLLLLLQ SGSKRDSLSK RCLLLGHSLF TELTGRIEKL
     VVSVQPFCFI ILGLCIVGMY LKLLLPMYSM MQGI
//