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Database: UniProt
Entry: D4ZZM9_ARTPN
LinkDB: D4ZZM9_ARTPN
Original site: D4ZZM9_ARTPN 
ID   D4ZZM9_ARTPN            Unreviewed;       453 AA.
AC   D4ZZM9;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   05-JUL-2017, entry version 50.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:BAI88553.1};
GN   ORFNames=NIES39_A07150 {ECO:0000313|EMBL:BAI88553.1};
OS   Arthrospira platensis (strain NIES-39 / IAM M-135) (Spirulina
OS   platensis).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Microcoleaceae; Arthrospira.
OX   NCBI_TaxID=696747 {ECO:0000313|EMBL:BAI88553.1, ECO:0000313|Proteomes:UP000006803};
RN   [1] {ECO:0000313|EMBL:BAI88553.1, ECO:0000313|Proteomes:UP000006803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-39 / IAM M-135 {ECO:0000313|Proteomes:UP000006803};
RX   PubMed=20203057; DOI=10.1093/dnares/dsq004;
RA   Fujisawa T., Narikawa R., Okamoto S., Ehira S., Yoshimura H.,
RA   Suzuki I., Masuda T., Mochimaru M., Takaichi S., Awai K., Sekine M.,
RA   Horikawa H., Yashiro I., Omata S., Takarada H., Katano Y., Kosugi H.,
RA   Tanikawa S., Ohmori K., Sato N., Ikeuchi M., Fujita N., Ohmori M.;
RT   "Genomic structure of an economically important cyanobacterium,
RT   Arthrospira (Spirulina) platensis NIES-39.";
RL   DNA Res. 17:85-103(2010).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP011615; BAI88553.1; -; Genomic_DNA.
DR   RefSeq; WP_006618872.1; NC_016640.1.
DR   STRING; 696747.NIES39_A07150; -.
DR   EnsemblBacteria; BAI88553; BAI88553; NIES39_A07150.
DR   KEGG; arp:NIES39_A07150; -.
DR   PATRIC; fig|696747.3.peg.776; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006803; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006803};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006803}.
FT   DOMAIN      149    277       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      358    427       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     157    164       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   453 AA;  51038 MW;  B222A9970CC0F1A4 CRC64;
     MDISVEQLWN QVLERLQLQL GEPTYNTWIK TAIATSLENH CLVISTANPF ACNWLQKHYR
     EIIADVVQDI LGDRLEICIT TGTGELVTID HHNPRVSSSG LDTVGEVVPT VHKPPHLNSK
     YMFSQFVVGA GSRLAHAASL AVAESPGREF NPLFLCGGVG LGKTHLMQAI GHYRLEINPL
     ARVFYVSTEK FTNDLITAIR RDSMQSFRDH YRAADVLLVD DIQFIEGKEY TQEEFFHTFN
     TLHEAGKQIV LASDRPPTKI SGLQDRLCSR FSMGLVADIQ PPDLETRMAI LQKKAEYENM
     RLPPAVIEYI ATNYTSNIRE LEGALIRAVA YISISSLPMT VENIAAVLTP KEQRSESSPE
     IVIQAVAEKF KVSVEDLKGH SRRREISLAR QVGMYLMRQH TDLSLPKIGE VFGGKDHTTV
     MYGCEKITKR RDRDSELHQI LQQLSDRINL NSR
//
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