ID D5EEK6_AMICL Unreviewed; 460 AA.
AC D5EEK6;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:ADE56988.1};
GN OrderedLocusNames=Amico_0856 {ECO:0000313|EMBL:ADE56988.1};
OS Aminobacterium colombiense (strain DSM 12261 / ALA-1).
OC Bacteria; Synergistota; Synergistia; Synergistales; Aminobacteriaceae;
OC Aminobacterium.
OX NCBI_TaxID=572547 {ECO:0000313|EMBL:ADE56988.1, ECO:0000313|Proteomes:UP000002366};
RN [1] {ECO:0000313|EMBL:ADE56988.1, ECO:0000313|Proteomes:UP000002366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12261 / ALA-1 {ECO:0000313|Proteomes:UP000002366};
RX PubMed=21304712;
RA Chertkov O., Sikorski J., Brambilla E., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Nolan M., Lucas S., Tice H., Cheng J.F., Han C.,
RA Detter J.C., Bruce D., Tapia R., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Spring S.,
RA Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Aminobacterium colombiense type strain (ALA-
RT 1).";
RL Stand. Genomic Sci. 2:280-289(2010).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP001997; ADE56988.1; -; Genomic_DNA.
DR RefSeq; WP_013048254.1; NC_014011.1.
DR AlphaFoldDB; D5EEK6; -.
DR STRING; 572547.Amico_0856; -.
DR KEGG; aco:Amico_0856; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_1_0_0; -.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000002366; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000002366}.
FT DOMAIN 21..78
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 116..213
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 221..452
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 460 AA; 50169 MW; 310276CB87981D2C CRC64;
MSHLALKEAL ESLHRHDIDF ADLFFESSSF HSSSFEDKTM EEISTSLREG VGARILFNDL
TSFAHMPGVT LKDGLTALQE AALNMGIIIP STTLDNNLLE RVVREVIPPQ PADQKFFHYI
DQALRQKSSL VTQVSINYTL SSRQIAIIND KGELRKDERA YTSFSVEVVV EKEEQIQTGY
ESAARAESPD LFWQHHDPDA LAQRALDEAL LMLDAPDCPA GTMPVLLSGE AGGTLIHEAC
GHGLEADIIQ KDYSVYRNKL GEKVASPLVT MIDDGTISGL YGSYSIDDEG MPAKRTVLIE
NGILKAYLTD MVSSKKDNLP LSGNGRRSSY RNPPIPRMSN TFILPGNNEP EEMIKGIDYG
LYVKRMGGGE VNPTTGDFVF QVTEGYLIQR GSIIHPVKGA LLTGNGPEAL MDIVGVGKDL
HFLPGTCGKA GQSVPVTDGQ PSLLIKKMTV GGSSTDHETL
//
