ID D5FV17_PHYAN Unreviewed; 241 AA.
AC D5FV17;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Homeobox-leucine zipper protein {ECO:0000256|RuleBase:RU369038};
DE AltName: Full=HD-ZIP protein {ECO:0000256|RuleBase:RU369038};
DE AltName: Full=Homeodomain transcription factor {ECO:0000256|RuleBase:RU369038};
GN Name=HB-12 {ECO:0000313|EMBL:ACZ05048.1};
OS Phytolacca acinosa (Indian pokeweed) (Phytolacca esculenta).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC Caryophyllales; Phytolaccaceae; Phytolacca.
OX NCBI_TaxID=3528 {ECO:0000313|EMBL:ACZ05048.1};
RN [1] {ECO:0000313|EMBL:ACZ05048.1}
RP NUCLEOTIDE SEQUENCE.
RA Liu H., Zhao H., Chai T., Zhang Y.;
RT "Cloning of the PAHB-12 gene from Phytolacca acinosa under cadmium
RT stress.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor. {ECO:0000256|RuleBase:RU369038}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000256|ARBA:ARBA00025748, ECO:0000256|RuleBase:RU369038}.
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DR EMBL; FJ861306; ACZ05048.1; -; mRNA.
DR AlphaFoldDB; D5FV17; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; HOMEOBOX-LEUCINE ZIPPER PROTEIN; 1.
DR PANTHER; PTHR24326:SF122; HOMEOBOX-LEUCINE ZIPPER PROTEIN ATHB-7; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Transcription {ECO:0000256|RuleBase:RU369038};
KW Transcription regulation {ECO:0000256|RuleBase:RU369038}.
FT DOMAIN 21..81
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 23..82
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 241 AA; 27421 MW; B71766CDFB4D0AD5 CRC64;
MMVEEGEYYS PSEVGSGSSM KRKMMNKKRF SDEQVKSLES IFENETKLEP KKKVQVAREL
GLQPRQVAIW FQNKRARFKS KQLERDYSLL RTSYNSLASQ FETLKKDKLS ILSQLQKLRK
ELEIRGGNTS NDESSESEEK KSESENTNKT DQLEEKPALS VEGSEYGASI LSDEGSSENT
NYFRVQGETD PDDMDILAMV PPSGLTSGEA WDQGLFDQAL PQAGADSNSQ WWDFWSQVII
E
//
