ID D5GIC7_TUBMM Unreviewed; 608 AA.
AC D5GIC7;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 08-NOV-2023, entry version 55.
DE SubName: Full=(Perigord truffle) hypothetical protein {ECO:0000313|EMBL:CAZ84270.1};
GN ORFNames=GSTUM_00008427001 {ECO:0000313|EMBL:CAZ84270.1};
OS Tuber melanosporum (strain Mel28) (Perigord black truffle).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Tuberaceae; Tuber.
OX NCBI_TaxID=656061 {ECO:0000313|EMBL:CAZ84270.1, ECO:0000313|Proteomes:UP000006911};
RN [1] {ECO:0000313|EMBL:CAZ84270.1, ECO:0000313|Proteomes:UP000006911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mel28 {ECO:0000313|EMBL:CAZ84270.1,
RC ECO:0000313|Proteomes:UP000006911};
RX PubMed=20348908; DOI=10.1038/nature08867;
RA Martin F., Kohler A., Murat C., Balestrini R., Coutinho P.M., Jaillon O.,
RA Montanini B., Morin E., Noel B., Percudani R., Porcel B., Rubini A.,
RA Amicucci A., Amselem J., Anthouard V., Arcioni S., Artiguenave F.,
RA Aury J.M., Ballario P., Bolchi A., Brenna A., Brun A., Buee M.,
RA Cantarel B., Chevalier G., Couloux A., Da Silva C., Denoeud F.,
RA Duplessis S., Ghignone S., Hilselberger B., Iotti M., Marcais B., Mello A.,
RA Miranda M., Pacioni G., Quesneville H., Riccioni C., Ruotolo R.,
RA Splivallo R., Stocchi V., Tisserant E., Viscomi A.R., Zambonelli A.,
RA Zampieri E., Henrissat B., Lebrun M.H., Paolocci F., Bonfante P.,
RA Ottonello S., Wincker P.;
RT "Perigord black truffle genome uncovers evolutionary origins and mechanisms
RT of symbiosis.";
RL Nature 464:1033-1038(2010).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR EMBL; FN430326; CAZ84270.1; -; Genomic_DNA.
DR RefSeq; XP_002840079.1; XM_002840033.1.
DR AlphaFoldDB; D5GIC7; -.
DR STRING; 656061.D5GIC7; -.
DR EnsemblFungi; CAZ84270; CAZ84270; GSTUM_00008427001.
DR GeneID; 9184628; -.
DR KEGG; tml:GSTUM_00008427001; -.
DR eggNOG; KOG1978; Eukaryota.
DR HOGENOM; CLU_449183_0_0_1; -.
DR InParanoid; D5GIC7; -.
DR OMA; WINTEHE; -.
DR OrthoDB; 1369806at2759; -.
DR Proteomes; UP000006911; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF41; MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000006911}.
FT DOMAIN 222..361
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 390..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 65565 MW; C126E0B20CADC2D6 CRC64;
MGIQALPDTA VRALGSGQVL TDPVSLIKEL LDNSLDALAT AISIEVSQNT LDVLQVKDNG
HGIPTEDREF VAMRHCTSKI TDFEEIQDCR SLGFRGEALA SAAELAGGLV ITTMVEGEKV
AMACTCDRVG KVTARKPVGA MKGTTVRVTD FFKFLPVRRE NAIKGAQKSL SKVRTLLQRY
YLSHPACRFS LRVLAPPQKS KAAGGQSEDI VYAPSKSVSE AVMKAVGKEI VATCQWINTE
HEEVTDGSGE QKIGIEAFMP KPGSDPAIIC RKPQCTNFVF VDSRPVSCAR GTLKQILSLY
KSYLKSALPD SAISDPFLYL NLRCPPGAYD PNIEPAKDDV MFFHADRVIG AVEVIFKGLY
GELKTKSSPG GSGGKGKSVE MMTGGFELLL ARKRDPKPGT TKPPEAPEID EDEEEMAAQQ
VNMMMELDED PPAAGLTPAN PGKAPPVQTR EESPHRSHNR DGSVRPPMFS ITDAPSPGSV
RPGELNQEPT PPAAPLAQMV QTPRRRPTNW GFNMSSGYDE DESDLVLDEV ERQVRSDLAE
EQADEAAARD IAISNPWTAA KMNSPASGSN QPFSPAIVPS IWSSTVSSLL CDSCIVLATD
DHNAPNSK
//
