ID D5L2X4_VOLCA Unreviewed; 133 AA.
AC D5L2X4;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Sphingomyelin synthase-like domain-containing protein {ECO:0000259|Pfam:PF14360};
DE Flags: Fragment;
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|EMBL:ADF43112.1};
RN [1] {ECO:0000313|EMBL:ADF43112.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Eve {ECO:0000313|EMBL:ADF43112.1}, and Poona
RC {ECO:0000313|EMBL:ADF43113.1};
RX PubMed=20395508; DOI=10.1126/science.1186222;
RA Ferris P., Olson B.J., De Hoff P.L., Douglass S., Casero D., Prochnik S.,
RA Geng S., Rai R., Grimwood J., Schmutz J., Nishii I., Hamaji T., Nozaki H.,
RA Pellegrini M., Umen J.G.;
RT "Evolution of an expanded sex-determining locus in Volvox.";
RL Science 328:351-354(2010).
RN [2] {ECO:0000313|EMBL:ADF43112.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Eve {ECO:0000313|EMBL:ADF43112.1}, and Poona
RC {ECO:0000313|EMBL:ADF43113.1};
RA Ferris P.J., Umen J.G.;
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC {ECO:0000256|ARBA:ARBA00005441}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GU735472; ADF43112.1; -; Genomic_DNA.
DR EMBL; GU735473; ADF43113.1; -; Genomic_DNA.
DR AlphaFoldDB; D5L2X4; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR045221; Sphingomyelin_synth-like.
DR InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR PANTHER; PTHR21290:SF62; PHOSPHATIDYLINOSITOL:CERAMIDE INOSITOLPHOSPHOTRANSFERASE 1; 1.
DR PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR Pfam; PF14360; PAP2_C; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..112
FT /note="Sphingomyelin synthase-like"
FT /evidence="ECO:0000259|Pfam:PF14360"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADF43112.1"
FT NON_TER 133
FT /evidence="ECO:0000313|EMBL:ADF43112.1"
SQ SEQUENCE 133 AA; 15047 MW; 9512B80204594B9D CRC64;
SVTQLPGPSF HCRANAPSAR RPWPAHWSGH LVVDVGRQVS KSCGDLIFSS HTTFILTGIL
AYNEYGFLRA MKAMSWLLGV VLSILIVASR KHYTVDVIIA WYTVPLVFYM MYRRWTTRRP
MSDFIGDAPV PAF
//
