ID   D5LTX7_9ESCH            Unreviewed;       175 AA.
AC   D5LTX7;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030904};
DE   Flags: Fragment;
GN   Name=metG {ECO:0000313|EMBL:ADF45033.1};
OS   Escherichia sp. TW14263.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=754337 {ECO:0000313|EMBL:ADF45033.1};
RN   [1] {ECO:0000313|EMBL:ADF45033.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TW14263 {ECO:0000313|EMBL:ADF45033.1};
RA   Walk S.T., Alm E.W., Gordon D.M., Ram J.L., Toranzos G.A., Tiedje J.M.,
RA   Whittam T.S.;
RT   "Cryptic Lineages of the Genus Escherichia.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-
CC         methionyl-tRNA(Met); Xref=Rhea:RHEA:13481, Rhea:RHEA-COMP:9667,
CC         Rhea:RHEA-COMP:9698, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57844, ChEBI:CHEBI:78442, ChEBI:CHEBI:78530,
CC         ChEBI:CHEBI:456215; EC=6.1.1.10;
CC         Evidence={ECO:0000256|ARBA:ARBA00001234};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GU969783; ADF45033.1; -; Genomic_DNA.
DR   AlphaFoldDB; D5LTX7; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 2.20.28.20; Methionyl-tRNA synthetase, Zn-domain; 1.
DR   InterPro; IPR023458; Met-tRNA_ligase_1.
DR   InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR   InterPro; IPR029038; MetRS_Zn.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR45765; METHIONINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR45765:SF1; METHIONINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR   Pfam; PF09334; tRNA-synt_1g; 1.
DR   SUPFAM; SSF57770; Methionyl-tRNA synthetase (MetRS), Zn-domain; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE   4: Predicted;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000313|EMBL:ADF45033.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT   DOMAIN          1..175
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADF45033.1"
FT   NON_TER         175
FT                   /evidence="ECO:0000313|EMBL:ADF45033.1"
SQ   SEQUENCE   175 AA;  20014 MW;  2990FD888DE9EE72 CRC64;
     ADVWVRYQRM RGHEVNFICA DDAHGTPIML KAQQLGISPE QMIGEMSQEH QTDFAGFNIS
     YDNYHSTHSE ENRQLSELIY TRLKENGFIK NRTISQLYDP EKGMFLPDRF VKGTCPKCKA
     PDQYGDNCEV CGATYSPTEL IEPKSVVSGA TPVMRDSEHF FFDLPSFSEM LQAWT
//