ID D5PCL8_9MYCO Unreviewed; 375 AA.
AC D5PCL8;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:EFG76191.1};
DE EC=1.1.1.205 {ECO:0000313|EMBL:EFG76191.1};
GN Name=guaB3 {ECO:0000313|EMBL:EFG76191.1};
GN ORFNames=HMPREF0591_3912 {ECO:0000313|EMBL:EFG76191.1};
OS Mycobacterium parascrofulaceum ATCC BAA-614.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=525368 {ECO:0000313|EMBL:EFG76191.1, ECO:0000313|Proteomes:UP000003653};
RN [1] {ECO:0000313|EMBL:EFG76191.1, ECO:0000313|Proteomes:UP000003653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-614 {ECO:0000313|EMBL:EFG76191.1,
RC ECO:0000313|Proteomes:UP000003653};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG76191.1}.
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DR EMBL; ADNV01000277; EFG76191.1; -; Genomic_DNA.
DR RefSeq; WP_007167940.1; NZ_GG770553.1.
DR AlphaFoldDB; D5PCL8; -.
DR eggNOG; COG0516; Bacteria.
DR HOGENOM; CLU_064068_0_0_11; -.
DR Proteomes; UP000003653; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:EFG76191.1}.
FT DOMAIN 17..302
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 375 AA; 39166 MW; 2EE057BB340E35D2 CRC64;
MVEIGMGRNA RRTYELSEVS IVPSRRTRSS QDVSTAWQLD AYRFEIPVVA HPTDALVSPE
FAIELGRLGG LGVLNGEGLI GRHADVEAKI AQLVEAATKE PEPSASIRLL QELHAAPLNP
DLLGSAVARI REAGVTTAVR VSPQNAQALT PVLLQAGIDL LVIQGTIVSA ERVASDGEPL
NLKTFISELD VPVVAGGVLD HRTALHLMRT GAAGVIVGYG STRGVTTSDE VLGISVPMAT
AIADAAAARR EYLDETGGRY VHVLADGDIH TSGELAKAIA CGADAVVLGT PLAESAEALG
EGWFWPAAAA HPSLPRGALL QIALGERPPL ERVLNGPSDD PFGSLNLVGG LRRSMAKAGY
CDLKEFQKVG LTVGG
//
