ID D5PFX3_9MYCO Unreviewed; 494 AA.
AC D5PFX3;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Aldehyde dehydrogenase (NAD) family protein {ECO:0000313|EMBL:EFG75047.1};
DE EC=1.2.1.- {ECO:0000313|EMBL:EFG75047.1};
GN Name=aldA6 {ECO:0000313|EMBL:EFG75047.1};
GN ORFNames=HMPREF0591_5067 {ECO:0000313|EMBL:EFG75047.1};
OS Mycobacterium parascrofulaceum ATCC BAA-614.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=525368 {ECO:0000313|EMBL:EFG75047.1, ECO:0000313|Proteomes:UP000003653};
RN [1] {ECO:0000313|EMBL:EFG75047.1, ECO:0000313|Proteomes:UP000003653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-614 {ECO:0000313|EMBL:EFG75047.1,
RC ECO:0000313|Proteomes:UP000003653};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG75047.1}.
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DR EMBL; ADNV01000340; EFG75047.1; -; Genomic_DNA.
DR RefSeq; WP_007169056.1; NZ_GG770554.1.
DR AlphaFoldDB; D5PFX3; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_0_0_11; -.
DR Proteomes; UP000003653; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07089; ALDH_CddD-AldA-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 20..489
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 264
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 494 AA; 53414 MW; 43E20178D97F189A CRC64;
MTEAVKVRFE PKMMIDGKLV DGQAGTFTNI NPATEEPLGE VADASKEDMH RAIDAARRAF
DETDWSTNRE LRKRCLLQLH EAIESEKEEL REELILEVGS PRAITFGPQL DAPLEDGLRY
PARLIDEYAW ETDLGDKVIS LTGTLTTRKV WREPVGVVGA IVPWNFPFEV TINKLGQALG
TGNTVVLKPA PNTPFNATRL GRLIAEKTDI PPGVVNVVTA SDHFVGEELT LSPKVDLISF
TGSTVVGQRI MEKGAATMKR LFLELGGKSA TIVLEDADFG MACAIGIAPC MHAGQGCANP
TRMLLPRSRY DEGVEILKSI YENVTCADPQ DPGTLCGPVI SEVQRNRVMG YIRKGVEEGA
TALVGGPDAP TGFDKGFYVR PTLFTDVDNS MTIAQEEIFG PVLCVIPFDD EEDAIRIAND
SKYGLAGNVM SGSLERSLAV ARRIRAGFMG VNGGAPYGAD TPFGGYKYSG VGRQNGIAGF
DQYTEIKSVA YPAG
//
