ID D5VK61_CAUST Unreviewed; 265 AA.
AC D5VK61;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=Cseg_2429 {ECO:0000313|EMBL:ADG10884.1};
OS Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 /
OS LMG 17158 / TK0059) (Mycoplana segnis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=509190 {ECO:0000313|EMBL:ADG10884.1, ECO:0000313|Proteomes:UP000002629};
RN [1] {ECO:0000313|Proteomes:UP000002629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 /
RC TK0059 {ECO:0000313|Proteomes:UP000002629};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP002008; ADG10884.1; -; Genomic_DNA.
DR RefSeq; WP_013079537.1; NC_014100.1.
DR AlphaFoldDB; D5VK61; -.
DR STRING; 509190.Cseg_2429; -.
DR KEGG; cse:Cseg_2429; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_0_0_5; -.
DR Proteomes; UP000002629; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 32..154
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 265 AA; 28473 MW; 936E4D6E3E7F90A5 CRC64;
MSKGNVLVVG SNATRIEIQG GGTGPTGQYL NELVVPVMAL LAAGYDITFA TPDGTKPFID
PVSDQTVHFD NDEAAHKRAQ DFFANDRAMN SVKTLRAVLD GGLDQYVAFF TPGGQAPVVD
LMQDPELGEI LRHFHAHKKP SAFLCHGPIA SISAMQHARE FRAALIAGDT PKAAKLAQGW
PYAGYRMTVY SSSEEKPIED NILHGKLYFH MPEALTTAGG VVDVGPDFAP HVVEDRELIT
GQNPRSDHQI GKALVAALSR VSVDA
//
