ID D5VMX8_CAUST Unreviewed; 460 AA.
AC D5VMX8;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Transcriptional regulator, GntR family with aminotransferase domain {ECO:0000313|EMBL:ADG11851.1};
GN OrderedLocusNames=Cseg_3419 {ECO:0000313|EMBL:ADG11851.1};
OS Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 /
OS LMG 17158 / TK0059) (Mycoplana segnis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=509190 {ECO:0000313|EMBL:ADG11851.1, ECO:0000313|Proteomes:UP000002629};
RN [1] {ECO:0000313|Proteomes:UP000002629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 /
RC TK0059 {ECO:0000313|Proteomes:UP000002629};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP002008; ADG11851.1; -; Genomic_DNA.
DR RefSeq; WP_013080498.1; NC_014100.1.
DR AlphaFoldDB; D5VMX8; -.
DR STRING; 509190.Cseg_3419; -.
DR KEGG; cse:Cseg_3419; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_5; -.
DR Proteomes; UP000002629; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:ADG11851.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:ADG11851.1}.
FT DOMAIN 14..82
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 460 AA; 47667 MW; CEBE4873F8BA7399 CRC64;
MAAPWTPDLP AGEGPLYERL VAALRSDIAS GALAAGARLP PQRDLAYRLG IGLGTVTRAY
VEAEKAGLVS AHVGRGSFVN APADHRAPVR EGPVNLAQNI APAGPAASRI AEAMARLRRR
PDLLEHLAYA PAAGHEAQRR AGAQWLQRFG GFDGADVSRL VCCGGAQQGL ALAMGAVARA
GDAVLCEAST YNGVKALAAH MGLRPQGVAL DEEGLAADAL EAAVKATGAR VLSVIPTLQN
PTGRIMSVSR REAIAALARR LDLTIIEDDI YGAYAPNAPP PLALLAPERT FHVSGVSKTL
GPGLRAGFLV APTEAAFERV LDAVRALTYA PSGFGGLVAT QWIEDGAADQ IVAEVREEAA
ARLSLARDIL GSAIEPPRSD CAPHVWLPMS ELEAERLAGR ALRGGAEVTP PDAPIVTPGL
VTGVRVCLGA APDRQTLRQG LEIVAGALSS EVGERSRAVI
//
