ID D5X5E8_THIK1 Unreviewed; 325 AA.
AC D5X5E8;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Regulatory protein MerR {ECO:0000313|EMBL:ADG31841.1};
GN OrderedLocusNames=Tint_2500 {ECO:0000313|EMBL:ADG31841.1};
OS Thiomonas intermedia (strain K12) (Thiobacillus intermedius).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Thiomonas.
OX NCBI_TaxID=75379 {ECO:0000313|EMBL:ADG31841.1};
RN [1] {ECO:0000313|EMBL:ADG31841.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 {ECO:0000313|EMBL:ADG31841.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ovchinnikova G., Kerfeld C.A., Cannon G.C.,
RA Heinhorst S., Woyke T.;
RT "Complete sequence of Thiomonas intermedia K12.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002021; ADG31841.1; -; Genomic_DNA.
DR AlphaFoldDB; D5X5E8; -.
DR STRING; 75379.Tint_2500; -.
DR KEGG; tin:Tint_2500; -.
DR eggNOG; COG0789; Bacteria.
DR eggNOG; COG5012; Bacteria.
DR HOGENOM; CLU_045945_3_0_4; -.
DR BioCyc; TINT75379:TINT_RS12520-MONOMER; -.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01104; HTH_MlrA-CarA; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR036594; Meth_synthase_dom.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
FT DOMAIN 11..66
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 198..325
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 325 AA; 35797 MW; 42254E9C9F3F21CC CRC64;
MNDRTVNTAL QLSIAAVERD TGIGKDTLRV WERRYGFPQP HRDASGDRLY PLDQVERLRV
IKRLLDGGHR PAQVVALPID ELDALARGRS SAEISPDAAA ASASEQMPTE SAEVHAYLAL
LKRHDAELLR RALLQDAMRM GISRFVTEVV APLNYGVGQA WMRGELEVFE EHLYSEVIQR
VLRTAIDAIP LGEAAQSRPK VLMTTVPQEP HVLGLLMAEA MLALEGCRCV QLGAQLPLGN
MLMAAQAHAA DVLVLSFSSL LQAAQVFDAL AELRDRLPRA VELWAGGSNP ALRKRLPEGV
RVTAALTDLA HSVHDWRERH RVSGF
//
