ID D6AQN1_STRFL Unreviewed; 952 AA.
AC D6AQN1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:EFE75814.2};
GN ORFNames=SSGG_03181 {ECO:0000313|EMBL:EFE75814.2};
OS Streptomyces filamentosus NRRL 15998.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=457431 {ECO:0000313|EMBL:EFE75814.2, ECO:0000313|Proteomes:UP000003986};
RN [1] {ECO:0000313|Proteomes:UP000003986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RA Molnar K.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 15998 {ECO:0000313|Proteomes:UP000003986};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Ward D., Young S., Kodira C.D., Zeng Q., Koehrsen M.,
RA Godfrey P., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland B.L.C., Ilzarbe M.,
RA Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces roseosporus strain NRRL 15998.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS999644; EFE75814.2; -; Genomic_DNA.
DR AlphaFoldDB; D6AQN1; -.
DR Proteomes; UP000003986; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EFE75814.2};
KW Hydrolase {ECO:0000313|EMBL:EFE75814.2};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 83..247
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 275..442
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 713..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 873..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 952 AA; 105461 MW; 0154E6FC322E82CA CRC64;
MSTSFADLQS QLGQLSLRDA NRLGRRLEGA RRIRKPEARQ SVLDEIAAEA GKAADRLAAR
AARLPALSYP EELPVSQKKD EILEAIRDHQ VVIVAGETGS GKTTQIPKIC MELGRGVRGM
IGHTQPRRIA ARTVAERVAD ELKTPLGETV GWKVRFTDQV NPESTYLKLM TDGILLAEIQ
TDRELLAYDT IIIDEAHERS LNIDFLLGYL ARLLPRRPDL KVVITSATID PERFARHFGD
APIVEVSGRT YPVEVRYRPL LEEDSEDSDR DQITAICDAV DELGHEAPGD VLVFLSGERE
IRDTADALNK RNLRHTEVLP LYARLSHAEQ HRVFQRHTGR RIVLATNVAE TSLTVPGIKY
VIDPGNARIS RYSHRTKVQR LPIERISQAS ANQCKGRCGR TSDGICIRLY SEDDFVTRPE
FTDPEILRTN LASVILQMTA AGLGDIEKFP FIDPPDHRNI RDGVQLLQEL GALEQGEKSP
QEGKRGQRLT PLGRKLSQLP VDPRLARMVI EADKNGCVRE VMVIAAALSI QDPRERPAEK
QTQADQNHAR FKDETSDFLA YLNLWAYVRE QQKERGSSSF RRMCKQEYLN FLRIREWQDI
YAQLRTVAKQ MGITVEEPKA EASVPEQAVH TSLLAGLLSH IGLKDTEKNE YLGARSAKFA
IFPGSALFKK QPRFLMSAEL VETSRLWARV NAKVEPEWIE PLAHAPGEAH LQRTALGEGP
GGGDGVRAGH PLRRADRRPA QGQFRTYRPG GLAGSVHPQR PGRGRLAHPP PVLPRQPQTA
RRGRGVGAPG PSPRHPRGRR DPLRLLRPAH PGAHRLRRAL RLLVETQEAR GAGRARLRAL
HAHQRKGRGR HQGRLPGLLA AGEAQVQGDV PVRARRGRGR CDGARPAPGA QPGHRRGLRL
ADPGAARGGR HRADPLAAEA DPPALRPRPE LRGEVPRPGR PAPGAAAADP GA
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